25 Einträge gefunden

1. SHIP1 Is Present but Strongly Downregulated in T-ALL, and after Restoration Suppresses Leukemia Growth in a T-ALL Xenotransplantation Mouse Model

   1. Ehm, Patrick
   2. Rietow, Ruth
   3. Wegner, Wiebke
   4. Bußmann, Lara
   5. Kriegs, Malte
   6. Dierck, Kevin
   7. Horn, Stefan

   2023 - Forschungsinformationssystem des UKE - frei zugänglich
2. Akute lymphoblastische Leukämie

   1. Escherich, Gabriele
   2. Möricke, Anja
   3. Horstmann, Martin
   4. Schrappe, Martin

   2022 - Forschungsinformationssystem des UKE
3. IKZF1 Deletions with COBL Breakpoints Are Not Driven by RAG-Mediated Recombination Events in Acute Lymphoblastic Leukemia

   1. Lopes, Bruno A
   2. Meyer, Claus
   3. Barbosa, Thayana C
   4. Poubel, Caroline P
   5. Mansur, Marcela B
   6. Duployez, Nicolas
   7. Bashton, Matthew

   2019 - Forschungsinformationssystem des UKE - frei zugänglich
4. High sensitivity and clonal stability of the genomic fusion as single marker for response monitoring in ETV6-RUNX1-positive acute lymphoblastic leukemia

   1. Hoffmann, Jana
   2. Krumbholz, Manuela
   3. Gutiérrez, Helia Pimentel
   4. Fillies, Marion
   5. Szymansky, Annabell
   6. Bleckmann, Kirsten
   7. Zur Stadt, Udo

   2019 - Forschungsinformationssystem des UKE
5. Tumor suppressors BTG1 and IKZF1 cooperate during mouse leukemia development and increase relapse risk in B-cell precursor acute lymphoblastic leukemia patients

   1. Scheijen, Blanca
   2. Boer, Judith M
   3. Marke, Rene'
   4. Tijchon, Esther
   5. van Ingen Schenau, Dorette
   6. Waanders, Esme'
   7. van Emst, Liesbeth

   2017 - Forschungsinformationssystem des UKE - frei zugänglich
6. IL-7 Receptor Mutations and Steroid Resistance in Pediatric T cell Acute Lymphoblastic Leukemia: A Genome Sequencing Study

   1. Li, Yunlei
   2. Buijs-Gladdines, Jessica G C A M
   3. Canté-Barrett, Kirsten
   4. Stubbs, Andrew P
   5. Vroegindeweij, Eric M
   6. Smits, Willem K
   7. van Marion, Ronald

   2016 - Forschungsinformationssystem des UKE - frei zugänglich
7. COBL is a novel hotspot for IKZF1 deletions in childhood acute lymphoblastic leukemia

   1. Lopes, Bruno Almeida
   2. Meyer, Claus
   3. Barbosa, Thayana Conceição
   4. Stadt, Udo Zur
   5. Horstmann, Martin
   6. Venn, Nicola C
   7. Heatley, Susan

   2016 - Forschungsinformationssystem des UKE
8. Refinement of IKZF1 recombination hotspots in pediatric BCP-ALL patients.

   1. Meyer, Claus
   2. Zur Stadt, Udo
   3. Escherich, Gabriele
   4. Hofmann, Julia
   5. Binato, Renata
   6. Barbosa, Thayana da Conceição
   7. Emerenciano, Mariana

   2013 - Forschungsinformationssystem des UKE
9. Identification of germline susceptibility loci in ETV6-RUNX1-rearranged childhood acute lymphoblastic leukemia.

   1. Ellinghaus, E
   2. Stanulla, M
   3. Richter, G
   4. Ellinghaus, D
   5. Te Kronnie, G
   6. Cario, G
   7. Cazzaniga, G

   2012 - Forschungsinformationssystem des UKE
10. The significance of PTEN and AKT aberrations in pediatric T-cell acute lymphoblastic leukemia.

    1. Zuurbier, Linda
    2. Petricoin, Emanuel F
    3. Vuerhard, Maartje J
    4. Calvert, Valerie
    5. Kooi, Clarissa
    6. Buijs-Gladdines, Jessica G C A M
    7. Smits, Willem K

    2012 - Forschungsinformationssystem des UKE - frei zugänglich
11. Leukemia-associated mutations in SHIP1 inhibit its enzymatic activity, interaction with the GM-CSF receptor and Grb2, and its ability to inactivate PI3K/AKT signaling.

    1. Brauer, Helena
    2. Strauss, Julia
    3. Wegner, Wiebke
    4. Müller-Tidow, Carsten
    5. Horstmann, Martin
    6. Jücker, Manfred

    2012 - Forschungsinformationssystem des UKE
12. Quantification of minimal residual disease (MRD) in acute lymphoblastic leukemia (ALL) using amplicon-fusion-site polymerase chain reaction (AFS-PCR).

    1. Weber, Axel
    2. Taube, Sylvia
    3. Zur Stadt, Udo
    4. Horstmann, Martin
    5. Krohn, Knut
    6. Bradtke, Jutta
    7. Teigler-Schlegel, Andrea

    2012 - Forschungsinformationssystem des UKE - frei zugänglich
13. In vivo imaging enables high resolution preclinical trials on patients' leukemia cells growing in mice.

    1. Terziyska, Nadia
    2. Catarina, Castro Alves
    3. Groiss, Volker
    4. Schneider, Katja
    5. Farkasova, Katarina
    6. Ogris, Manfred
    7. Wagner, Ernst

    2012 - Forschungsinformationssystem des UKE - frei zugänglich
14. NOTCH1 and/or FBXW7 mutations predict for initial good prednisone response but not for improved outcome in pediatric T-cell acute lymphoblastic leukemia patients treated on DCOG or COALL protocols.

    1. Zuurbier, L
    2. Homminga, I
    3. Calvert, V
    4. Te Winkel, M L
    5. Buijs-Gladdines, J G C A M
    6. Kooi, C
    7. Smits, W K

    2010 - Forschungsinformationssystem des UKE
15. Cooperative genetic defects in TLX3 rearranged pediatric T-ALL.

    1. Van Vlierberghe, P
    2. Homminga, I
    3. Zuurbier, L
    4. Gladdines-Buijs, J
    5. van Wering, E R
    6. Horstmann, Martin
    7. Beverloo, H B

    2008 - Forschungsinformationssystem des UKE
16. Gene transfer of SHIP-1 inhibits proliferation of juvenile myelomonocytic leukemia cells carrying KRAS2 or PTPN11 mutations.

    1. Metzner, A
    2. Horstmann, Martin
    3. Fehse, Boris
    4. Ortmeyer, Gerhard
    5. Niemeyer, C M
    6. Stocking, C
    7. Mayr, Georg W.

    2007 - Forschungsinformationssystem des UKE
17. Quantitative multiplexed profiling of cellular signaling networks using phosphotyrosine-specific DNA-tagged SH2 domains.

    1. Dierck, Kevin
    2. Machida, Kazuya
    3. Voigt, Anja
    4. Thimm, Julian
    5. Horstmann, Martin
    6. Fiedler, Walter
    7. Mayer, Bruce J

    2006 - Forschungsinformationssystem des UKE
18. Amsacrine combined with etoposide and high-dose methylprednisolone as salvage therapy in acute lymphoblastic leukemia in children.

    1. Horstmann, Martin
    2. Hassenpflug, Wolf-Achim
    3. Udo, Zur Stadt
    4. Escherich, Gabriele
    5. Janka-Schaub, Gritta
    6. Kabisch, Hartmut

    2005 - Forschungsinformationssystem des UKE - frei zugänglich
19. Targeting FLT3 in primary MLL-gene-rearranged infant acute lymphoblastic leukemia.

    1. Stam, Ronald W
    2. Boer, den
    3. Monique, L
    4. Schneider, Pauline
    5. Horstmann, Martin
    6. Horstmann, Martin
    7. Beverloo, H Berna

    2005 - Forschungsinformationssystem des UKE
20. Critical role of CDK2 for melanoma growth linked to its melanocyte-specific transcriptional regulation by MITF.

    1. Du, Jinyan
    2. Widlund, Hans R
    3. Horstmann, Martin
    4. Ramaswamy, Sridhar
    5. Ross, Ken
    6. Huber, Wade E
    7. Nishimura, Emi K

    2004 - Forschungsinformationssystem des UKE