41 Einträge gefunden

1. The Functional Role of Extracellular Matrix Proteins in Cancer

   1. Popova, Nadezhda V
   2. Jücker, Manfred

   2022 - Forschungsinformationssystem des UKE - frei zugänglich
2. Investigation of the function of the PI3-Kinase / AKT signaling pathway for leukemogenesis and therapy of acute childhood lymphoblastic leukemia (ALL)

   1. Ehm, Patrick
   2. Grottke, Astrid
   3. Bettin, Bettina
   4. Jücker, Manfred

   2022 - Forschungsinformationssystem des UKE
3. AKT in Bone Metastasis of Solid Tumors: A Comprehensive Review

   1. Hinz, Nico
   2. Jücker, Manfred

   2021 - Forschungsinformationssystem des UKE - frei zugänglich
4. Circulating tumor cells as a promising target for individualized drug susceptibility tests in cancer therapy

   1. Smit, Daniel J
   2. Pantel, Klaus
   3. Jücker, Manfred

   2021 - Forschungsinformationssystem des UKE
5. Targeted PI3K/AKT-hyperactivation induces cell death in chronic lymphocytic leukemia

   1. Ecker, Veronika
   2. Stumpf, Martina
   3. Brandmeier, Lisa
   4. Neumayer, Tanja
   5. Pfeuffer, Lisa
   6. Engleitner, Thomas
   7. Ringshausen, Ingo

   2021 - Forschungsinformationssystem des UKE - frei zugänglich
6. AKT1 and PTEN show the highest affinities among phosphoinositide binding proteins for the second messengers PtdIns(3,4,5)P3 and PtdIns(3,4)P2

   1. Nelson, Nina
   2. Razeto, Adelia
   3. Gilardi, Alessia
   4. Grättinger, Mira
   5. Kirchmair, Johannes
   6. Jücker, Manfred

   2021 - Forschungsinformationssystem des UKE
7. Knockdown of AKT3 Activates HER2 and DDR Kinases in Bone-Seeking Breast Cancer Cells, Promotes Metastasis In Vivo and Attenuates the TGFβ/CTGF Axis

   1. Hinz, Nico
   2. Baranowsky, Anke
   3. Horn, Michael
   4. Kriegs, Malte
   5. Sibbertsen, Freya
   6. Smit, Daniel J
   7. Clezardin, Philippe

   2021 - Forschungsinformationssystem des UKE - frei zugänglich
8. The Role of mTOR Signaling as a Therapeutic Target in Cancer

   1. Popova, Nadezhda V
   2. Jücker, Manfred

   2021 - Forschungsinformationssystem des UKE - frei zugänglich
9. Combined Targeting of AKT and mTOR Inhibits Proliferation of Human NF1-Associated Malignant Peripheral Nerve Sheath Tumour Cells In Vitro but not in a Xenograft Mouse Model In Vivo

   1. Schulte, Alexander
   2. Ewald, Florian
   3. Spyra, Melanie
   4. Smit, Daniel J
   5. Jiang, Wei
   6. Salamon, Johannes
   7. Jücker, Manfred

   2020 - Forschungsinformationssystem des UKE
10. High Sensitivity of Circulating Tumor Cells Derived from a Colorectal Cancer Patient for Dual Inhibition with AKT and mTOR Inhibitors

    1. Smit, Daniel J
    2. Cayrefourcq, Laure
    3. Haider, Marie-Therese
    4. Hinz, Nico
    5. Pantel, Klaus
    6. Alix-Panabières, Catherine
    7. Jücker, Manfred

    2020 - Forschungsinformationssystem des UKE
11. Characterization of the substrate specificity of the inositol 5-phosphatase SHIP1

    1. Nelson, Nina
    2. Wundenberg, Torsten
    3. Lin, Hongying
    4. Rehbach, Christoph
    5. Horn, Stefan
    6. Windhorst, Sabine
    7. Jücker, Manfred

    2020 - Forschungsinformationssystem des UKE
12. PI3K/AKT/mTOR signaling as a molecular target in head and neck cancer

    1. Marquard, Franziska E
    2. Jücker, Manfred

    2020 - Forschungsinformationssystem des UKE
13. Ectopic Expression of Hematopoietic SHIP1 in Human Colorectal Cancer

    1. Schaks, Matthias
    2. Allgoewer, Kristina
    3. Nelson, Nina
    4. Ehm, Patrick
    5. Heumann, Asmus
    6. Ewald, Florian
    7. Schumacher, Udo

    2020 - Forschungsinformationssystem des UKE
14. Analysis of the FLVR motif of SHIP1 and its importance for the protein stability of SH2 containing signaling proteins

    1. Ehm, Patrick A H
    2. Lange, Fabiola
    3. Hentschel, Carolin
    4. Jepsen, Anneke
    5. Glück, Madeleine
    6. Nelson, Nina
    7. Bettin, Bettina

    2019 - Forschungsinformationssystem des UKE
15. Distinct functions of AKT isoforms in breast cancer: a comprehensive review

    1. Hinz, Nico
    2. Jücker, Manfred

    2019 - Forschungsinformationssystem des UKE - frei zugänglich
16. Nuclear accumulation of SHIP1 mutants derived from AML patients leads to increased proliferation of leukemic cells

    1. Nalaskowski, Marcus M
    2. Ehm, Patrick
    3. Rehbach, Christoph
    4. Nelson, Nina
    5. Täger, Maike
    6. Modest, Kathrin
    7. Jücker, Manfred

    2018 - Forschungsinformationssystem des UKE
17. Combined inhibition of GLI and FLT3 signaling leads to effective anti-leukemic effects in human acute myeloid leukemia

    1. Latuske, Emily-Marie
    2. Stamm, Hauke
    3. Klokow, Marianne
    4. Vohwinkel, Gabi
    5. Muschhammer, Jana
    6. Bokemeyer, Carsten
    7. Jücker, Manfred

    2017 - Forschungsinformationssystem des UKE
18. Tight Junction Proteins Claudin-1 and Occludin Are Important for Cutaneous Wound Healing

    1. Volksdorf, Thomas
    2. Heilmann , Janina
    3. Eming, Sabine A
    4. Schawjinski , Kathrin
    5. Zorn-Kruppa, Michaela
    6. Ueck, Christopher
    7. Vidal-Y-Sy, Sabine

    2017 - Forschungsinformationssystem des UKE
19. Akt isoform specific effects in ovarian cancer progression

    1. Linnerth-Petrik, Nicolle M
    2. Santry, Lisa A
    3. Moorehead, Roger
    4. Jücker, Manfred
    5. Wootton, Sarah K
    6. Petrik, Jim

    2016 - Forschungsinformationssystem des UKE
20. Dual Targeting of Akt and mTORC1 Impairs Repair of DNA Double-Strand Breaks and Increases Radiation Sensitivity of Human Tumor Cells

    1. Holler, Marina
    2. Grottke, Astrid
    3. Mueck, Katharina
    4. Manes, Julia
    5. Jücker, Manfred
    6. Rodemann, H Peter
    7. Toulany, Mahmoud

    2016 - Forschungsinformationssystem des UKE - frei zugänglich