12 Einträge gefunden

1. Investigation of the function of the PI3-Kinase / AKT signaling pathway for leukemogenesis and therapy of acute childhood lymphoblastic leukemia (ALL)

   1. Ehm, Patrick
   2. Grottke, Astrid
   3. Bettin, Bettina
   4. Jücker, Manfred

   2022 - Forschungsinformationssystem des UKE
2. Cerebral metastasis in recurrent squamous cell carcinoma of the vulva: case report and review of the literature

   1. Jaeger, Anna
   2. Biermann, Maxine
   3. Prieske, Katharina
   4. Grimm, Donata
   5. Grottke, Astrid
   6. Salamon, Johannes
   7. Petersen, Cordula

   2020 - Forschungsinformationssystem des UKE
3. Zerebrale Metastasierung beim Mammakarzinom

   1. Muller , Volkmar
   2. Laakmann, Elena
   3. Grottke, Astrid
   4. Riecke, Kerstin
   5. Witzel, Isabell

   2018 - Forschungsinformationssystem des UKE
4. PTEN mediates the cross talk between breast and glial cells in brain metastases leading to rapid disease progression

   1. Hohensee, Ina
   2. Chuang, Han-Ning
   3. Grottke, Astrid
   4. Werner, Stefan
   5. Schulte, Alexander
   6. Horn, Stefan
   7. Lamszus, Katrin

   2017 - Forschungsinformationssystem des UKE
5. Akt1 and Akt3 but not Akt2 through interaction with DNA-PKcs stimulate proliferation and post-irradiation cell survival of K-RAS-mutated cancer cells

   1. Toulany, Mahmoud
   2. Maier, Julia
   3. Iida, Mari
   4. Rebholz, Simone
   5. Holler, Marina
   6. Grottke, Astrid
   7. Jüker, Manfred

   2017 - Forschungsinformationssystem des UKE - frei zugänglich
6. Dual Targeting of Akt and mTORC1 Impairs Repair of DNA Double-Strand Breaks and Increases Radiation Sensitivity of Human Tumor Cells

   1. Holler, Marina
   2. Grottke, Astrid
   3. Mueck, Katharina
   4. Manes, Julia
   5. Jücker, Manfred
   6. Rodemann, H Peter
   7. Toulany, Mahmoud

   2016 - Forschungsinformationssystem des UKE - frei zugänglich
7. Downregulation of AKT3 Increases Migration and Metastasis in Triple Negative Breast Cancer Cells by Upregulating S100A4

   1. Grottke, Astrid
   2. Ewald, Florian
   3. Lange, Tobias
   4. Nörz, Dominik
   5. Herzberger, Christiane
   6. Bach, Johanna
   7. Grabinski, Nicole

   2016 - Forschungsinformationssystem des UKE - frei zugänglich
8. ErbB2 signaling activates the Hedgehog pathway via PI3K-Akt in human esophageal adenocarcinoma: Identification of novel targets for concerted therapy concepts

   1. Kebenko, Maxim
   2. Drenckhan, Astrid
   3. Gros, Stephanie J
   4. Jücker, Manfred
   5. Grabinski, Nicole
   6. Ewald, Florian
   7. Grottke, Astrid

   2015 - Forschungsinformationssystem des UKE
9. Vertical Targeting of AKT and mTOR as Well as Dual Targeting of AKT and MEK Signaling Is Synergistic in Hepatocellular Carcinoma

   1. Ewald, Florian
   2. Nörz, Dominik
   3. Grottke, Astrid
   4. Bach, Johanna
   5. Herzberger, Christiane
   6. Hofmann, Bianca T
   7. Nashan, Björn

   2015 - Forschungsinformationssystem des UKE - frei zugänglich
10. Discontinuing MEK inhibitors in tumor cells with an acquired resistance increases migration and invasion

    1. Nörz, Dominik
    2. Grottke, Astrid
    3. Bach, Johanna
    4. Herzberger, Christiane
    5. Hofmann, Bianca T
    6. Nashan, Bjorn
    7. Jücker, Manfred

    2015 - Forschungsinformationssystem des UKE
11. Dual Inhibition of PI3K-AKT-mTOR- and RAF-MEK-ERK-signaling is synergistic in cholangiocarcinoma and reverses acquired resistance to MEK-inhibitors

    1. Ewald, Florian
    2. Nörz, Dominik
    3. Grottke, Astrid
    4. Hofmann, Bianca T
    5. Nashan, Björn
    6. Jücker, Manfred

    2014 - Forschungsinformationssystem des UKE
12. Combined targeting of AKT and mTOR using MK-2206 and RAD001 is synergistic in the treatment of cholangiocarcinoma

    1. Ewald, Florian
    2. Grabinski, Nicole
    3. Grottke, Astrid
    4. Windhorst, Sabine
    5. Nörz, Dominik
    6. Carstensen, Lisa
    7. Staufer, Katharina

    2013 - Forschungsinformationssystem des UKE