13 Einträge gefunden

1. Activated Src kinases downstream of BCR-ABL and Flt3 induces proteasomal degradation of SHIP1 by phosphorylation of tyrosine 1021

   1. Ehm, Patrick
   2. Bettin, Bettina
   3. Jücker, Manfred

   2023 - Forschungsinformationssystem des UKE
2. SHIP1 Is Present but Strongly Downregulated in T-ALL, and after Restoration Suppresses Leukemia Growth in a T-ALL Xenotransplantation Mouse Model

   1. Ehm, Patrick
   2. Rietow, Ruth
   3. Wegner, Wiebke
   4. Bußmann, Lara
   5. Kriegs, Malte
   6. Dierck, Kevin
   7. Horn, Stefan

   2023 - Forschungsinformationssystem des UKE - frei zugänglich
3. Reduced expression and activity of patient-derived SHIP1 phosphatase domain mutants

   1. Ehm, Patrick
   2. Nelson, Nina
   3. Giehler, Susanne
   4. Schaks, Matthias
   5. Bettin, Bettina
   6. Kirchmair, Johannes
   7. Jücker, Manfred

   2023 - Forschungsinformationssystem des UKE
4. JAK2-V617F is a negative regulation factor of SHIP1 protein and thus influences the AKT signaling pathway in patients with Myeloproliferative Neoplasm (MPN)

   1. Glück, Madeleine
   2. Dally, Lina
   3. Jücker, Manfred
   4. Ehm, Patrick

   2022 - Forschungsinformationssystem des UKE
5. Investigation of the function of the PI3-Kinase / AKT signaling pathway for leukemogenesis and therapy of acute childhood lymphoblastic leukemia (ALL)

   1. Ehm, Patrick
   2. Grottke, Astrid
   3. Bettin, Bettina
   4. Jücker, Manfred

   2022 - Forschungsinformationssystem des UKE
6. Combined Targeting of AKT and mTOR Synergistically Inhibits Formation of Primary Colorectal Carcinoma Tumouroids In Vitro: A 3D Tumour Model for Pre-therapeutic Drug Screening

   1. Nörz, Dominik
   2. Mullins, Christina S
   3. Smit, Daniel J
   4. Linnebacher, Michael
   5. Hagel, Grith
   6. Mirdogan, Alp
   7. Siekiera, Jacqueline

   2021 - Forschungsinformationssystem des UKE - frei zugänglich
7. Ectopic Expression of Hematopoietic SHIP1 in Human Colorectal Cancer

   1. Schaks, Matthias
   2. Allgoewer, Kristina
   3. Nelson, Nina
   4. Ehm, Patrick
   5. Heumann, Asmus
   6. Ewald, Florian
   7. Schumacher, Udo

   2020 - Forschungsinformationssystem des UKE
8. Nuclear accumulation of SHIP1 mutants derived from AML patients leads to increased proliferation of leukemic cells

   1. Nalaskowski, Marcus M
   2. Ehm, Patrick
   3. Rehbach, Christoph
   4. Nelson, Nina
   5. Täger, Maike
   6. Modest, Kathrin
   7. Jücker, Manfred

   2018 - Forschungsinformationssystem des UKE
9. Expression of Hedgehog Pathway Mediator GLI Represents a Negative Prognostic Marker in Human Acute Myeloid Leukemia and Its Inhibition Exerts Antileukemic Effects

   1. Wellbrock, Jasmin
   2. Latuske, Emily
   3. Köhler, Julian
   4. Wagner, Katharina
   5. Stamm, Hauke
   6. Vettorazzi, Eik
   7. Vohwinkel, Gabi

   2015 - Forschungsinformationssystem des UKE
10. The tumor suppressor SHIP1 colocalizes in nucleolar cavities with p53 and components of PML nuclear bodies

    1. Ehm, Patrick
    2. Nalaskowski, Marcus M
    3. Wundenberg, Torsten
    4. Jücker, Manfred

    2015 - Forschungsinformationssystem des UKE - frei zugänglich
11. Efficacious inhibition of Importin α/β-mediated nuclear import of human inositol phosphate multikinase

    1. Kublun, Inga
    2. Ehm, Patrick
    3. Brehm, Maria A
    4. Nalaskowski, Marcus M

    2014 - Forschungsinformationssystem des UKE
12. Nucleocytoplasmic shuttling of human inositol phosphate multikinase is influenced by CK2 phosphorylation.

    1. Meyer, Rüdiger
    2. Nalaskowski, Marcus
    3. Ehm, Patrick
    4. Schröder, Constantin
    5. Naj, Xenia
    6. Brehm, Maria
    7. Mayr, Georg W.

    2012 - Forschungsinformationssystem des UKE
13. A toolkit for graded expression of green fluorescent protein fusion proteins in mammalian cells.

    1. Nalaskowski, Marcus
    2. Ehm, Patrick
    3. Giehler, Susanne
    4. Mayr, Georg W.

    2012 - Forschungsinformationssystem des UKE