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Therapeutic shutdown of HBV transcripts promotes reappearance of the SMC5/6 complex and silencing of the viral genome in vivo
2022 - Forschungsinformationssystem des UKE - frei zugänglich
Efficacy of NVR 3-778, Alone and in Combination With Pegylated Interferon, vs Entecavir in uPA/SCID Mice With Humanized Livers and HBV Infection
2018 - Forschungsinformationssystem des UKE
Heme oxygenase-1 polymorphisms can affect HCV replication and treatment responses with different efficacy in humanized mice
2017 - Forschungsinformationssystem des UKE
Serum HBV pgRNA as a clinical marker for cccDNA activity
2017 - Forschungsinformationssystem des UKE
A Slow Maturation Process Renders Hepatitis B Virus Infectious
2016 - Forschungsinformationssystem des UKE
Primary Human Hepatocytes Repopulate Livers of Mice After In Vitro Culturing and Lentiviral-Mediated Gene Transfer
2016 - Forschungsinformationssystem des UKE
Hepatitis Delta co-infection in humanized mice leads to pronounced induction of innate immune responses in comparison to HBV mono-infection
2015 - Forschungsinformationssystem des UKE
Experimental Models: Cell Culture and Animal Models
2015 - Forschungsinformationssystem des UKE
Strong antiviral activity of the new l-hydroxycytidine derivative, l-Hyd4FC, in HBV-infected human chimeric uPA/SCID mice.
2012 - Forschungsinformationssystem des UKE
Selective induction of apoptosis by HMG-CoA reductase inhibitors in hepatoma cells and dependence on p53 expression.
2012 - Forschungsinformationssystem des UKE
Primary human hepatocytes from metabolic-disordered children recreate highly differentiated liver-tissue-like spheroids on alginate scaffolds.
2012 - Forschungsinformationssystem des UKE
Humanized chimeric uPA mouse model for the study of hepatitis B and D virus interactions and preclinical drug evaluation.
2012 - Forschungsinformationssystem des UKE
IFN-α inhibits HBV transcription and replication in cell culture and in humanized mice by targeting the epigenetic regulation of the nuclear cccDNA minichromosome.
2012 - Forschungsinformationssystem des UKE
Hepatitis B virus limits response of human hepatocytes to interferon-α in chimeric mice.
2011 - Forschungsinformationssystem des UKE
RGB marking facilitates multicolor clonal cell tracking.
2011 - Forschungsinformationssystem des UKE
In vivo proliferation of hepadnavirus-infected hepatocytes induces loss of covalently closed circular DNA in mice.
2010 - Forschungsinformationssystem des UKE
[Knowledge about HBV, prevention behaviour and treatment adherence of patients with chronic hepatitis B in a large referral centre in Germany].
2010 - Forschungsinformationssystem des UKE
Sequential combination therapy leads to biochemical and histological improvement despite low ongoing intrahepatic hepatitis B virus replication.
2008 - Forschungsinformationssystem des UKE
Virion half-life in chronic hepatitis B infection is strongly correlated with levels of viremia.
2008 - Forschungsinformationssystem des UKE
Prevention of hepatitis B virus infection in vivo by entry inhibitors derived from the large envelope protein.
2008 - Forschungsinformationssystem des UKE

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Therapeutic shutdown of HBV transcripts promotes reappearance of the SMC5/6 complex and silencing of the viral genome in vivo

Efficacy of NVR 3-778, Alone and in Combination With Pegylated Interferon, vs Entecavir in uPA/SCID Mice With Humanized Livers and HBV Infection

Heme oxygenase-1 polymorphisms can affect HCV replication and treatment responses with different efficacy in humanized mice

Serum HBV pgRNA as a clinical marker for cccDNA activity

A Slow Maturation Process Renders Hepatitis B Virus Infectious

Primary Human Hepatocytes Repopulate Livers of Mice After In Vitro Culturing and Lentiviral-Mediated Gene Transfer

Hepatitis Delta co-infection in humanized mice leads to pronounced induction of innate immune responses in comparison to HBV mono-infection

Experimental Models: Cell Culture and Animal Models

Strong antiviral activity of the new l-hydroxycytidine derivative, l-Hyd4FC, in HBV-infected human chimeric uPA/SCID mice.

Selective induction of apoptosis by HMG-CoA reductase inhibitors in hepatoma cells and dependence on p53 expression.

Primary human hepatocytes from metabolic-disordered children recreate highly differentiated liver-tissue-like spheroids on alginate scaffolds.

Humanized chimeric uPA mouse model for the study of hepatitis B and D virus interactions and preclinical drug evaluation.

IFN-α inhibits HBV transcription and replication in cell culture and in humanized mice by targeting the epigenetic regulation of the nuclear cccDNA minichromosome.

Hepatitis B virus limits response of human hepatocytes to interferon-α in chimeric mice.

RGB marking facilitates multicolor clonal cell tracking.

In vivo proliferation of hepadnavirus-infected hepatocytes induces loss of covalently closed circular DNA in mice.

[Knowledge about HBV, prevention behaviour and treatment adherence of patients with chronic hepatitis B in a large referral centre in Germany].

Sequential combination therapy leads to biochemical and histological improvement despite low ongoing intrahepatic hepatitis B virus replication.

Virion half-life in chronic hepatitis B infection is strongly correlated with levels of viremia.

Prevention of hepatitis B virus infection in vivo by entry inhibitors derived from the large envelope protein.