4 Einträge gefunden

1. Danusertib (formerly PHA-739358)--a novel combined pan-Aurora kinases and third generation Bcr-Abl tyrosine kinase inhibitor.

   1. Gontarewicz, Artur
   2. Brümmendorf, Tim

   2010 - Forschungsinformationssystem des UKE
2. Aurora kinase inhibitor PHA-739358 suppresses growth of hepatocellular carcinoma in vitro and in a xenograft mouse model.

   1. Benten, Daniel
   2. Keller, Gunhild
   3. Quaas, Alexander
   4. Schrader, Jörg
   5. Gontarewicz, Artur
   6. Balabanov, Stefan
   7. Balabanov, Melanie

   2009 - Forschungsinformationssystem des UKE - frei zugänglich
3. Simultaneous targeting of Aurora kinases and Bcr-Abl kinase by the small molecule inhibitor PHA-739358 is effective against imatinib-resistant BCR-ABL mutations including T315I.

   1. Gontarewicz, Artur
   2. Balabanov, Stefan
   3. von Amsberg, Gunhild
   4. Colombo, Riccardo
   5. Graziano, Alessio
   6. Pesenti, Enrico
   7. Benten, Daniel

   2008 - Forschungsinformationssystem des UKE
4. PHA-680626 exhibits anti-proliferative and pro-apoptotic activity on Imatinib-resistant chronic myeloid leukemia cell lines and primary CD34+ cells by inhibition of both Bcr-Abl tyrosine kinase and Aurora kinases.

   1. Gontarewicz, Artur
   2. Balabanov, Stefan
   3. von Amsberg, Gunhild
   4. Panse, Jens
   5. Schafhausen, Philippe
   6. Bokemeyer, Carsten
   7. Fiedler, Walter

   2008 - Forschungsinformationssystem des UKE