4 Einträge gefunden

1. Targeting aurora kinases with danusertib (PHA-739358) inhibits growth of liver metastases from gastroenteropancreatic neuroendocrine tumors in an orthotopic xenograft model.

   1. Fraedrich, Katharina
   2. Schrader, Jörg
   3. Ittrich, Harald
   4. von Amsberg, Gunhild
   5. Gontarewicz, Artur
   6. Matzat, Verena
   7. Kromminga, Arno

   2012 - Forschungsinformationssystem des UKE
2. Abcg2 overexpression represents a novel mechanism for acquired resistance to the multi-kinase inhibitor Danusertib in BCR-ABL-positive cells in vitro.

   1. Balabanov, Stefan
   2. Gontarewicz, Artur
   3. von Amsberg, Gunhild
   4. Raddrizzani, Laura
   5. Balabanov, Melanie
   6. Bosotti, Roberta
   7. Moll, Jürgen

   2011 - Forschungsinformationssystem des UKE - frei zugänglich
3. PHA-680626 exhibits anti-proliferative and pro-apoptotic activity on Imatinib-resistant chronic myeloid leukemia cell lines and primary CD34+ cells by inhibition of both Bcr-Abl tyrosine kinase and Aurora kinases.

   1. Gontarewicz, Artur
   2. Balabanov, Stefan
   3. von Amsberg, Gunhild
   4. Panse, Jens
   5. Schafhausen, Philippe
   6. Bokemeyer, Carsten
   7. Fiedler, Walter

   2008 - Forschungsinformationssystem des UKE
4. Simultaneous targeting of Aurora kinases and Bcr-Abl kinase by the small molecule inhibitor PHA-739358 is effective against imatinib-resistant BCR-ABL mutations including T315I.

   1. Gontarewicz, Artur
   2. Balabanov, Stefan
   3. von Amsberg, Gunhild
   4. Colombo, Riccardo
   5. Graziano, Alessio
   6. Pesenti, Enrico
   7. Benten, Daniel

   2008 - Forschungsinformationssystem des UKE