Induction chemotherapy before chemoradiotherapy and surgery for locally advanced rectal cancer : is it time for a randomized phase III trial?

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Autor/in:
Erscheinungsjahr:
2010
Medientyp:
Text
Schlagworte:
  • Humans
  • Randomized Controlled Trials as Topic
  • dosage
  • Combined Modality Therapy
  • Disease Progression
  • Clinical Trials, Phase II as Topic
  • Antineoplastic Combined Chemotherapy Protocols therapeutic use
  • Neoadjuvant Therapy
  • Neoplasm Staging
  • Chemotherapy, Adjuvant
  • Feasibility Studies
  • Radiotherapy, Adjuvant
  • Fluorouracil administration
  • Clinical Trials, Phase III as Topic
  • Rectal Neoplasms drug therapy
  • Rectum pathology
  • Humans
  • Randomized Controlled Trials as Topic
  • dosage
  • Combined Modality Therapy
  • Disease Progression
  • Clinical Trials, Phase II as Topic
  • Antineoplastic Combined Chemotherapy Protocols therapeutic use
  • Neoadjuvant Therapy
  • Neoplasm Staging
  • Chemotherapy, Adjuvant
  • Feasibility Studies
  • Radiotherapy, Adjuvant
  • Fluorouracil administration
  • Clinical Trials, Phase III as Topic
  • Rectal Neoplasms drug therapy
  • Rectum pathology
Beschreibung:
  • in the era of preoperative chemoradiotherapy (CRT) and total mesorectal excision (TME), the development of distant metastases is the predominant mode of failure in rectal cancer patients today. Integrating more effective systemic therapy into combined modality programs is the challenge. The question that needs to be addressed is how and when to apply systemic treatment with adequate dose and intensity.
  • in the era of preoperative chemoradiotherapy (CRT) and total mesorectal excision (TME), the development of distant metastases is the predominant mode of failure in rectal cancer patients today. Integrating more effective systemic therapy into combined modality programs is the challenge. The question that needs to be addressed is how and when to apply systemic treatment with adequate dose and intensity.
Lizenz:
  • info:eu-repo/semantics/restrictedAccess
Quellsystem:
Forschungsinformationssystem des UKE

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oai:pure.atira.dk:publications/ab8dca72-06a1-4ced-b1e2-2b9d5736ec79