Among the personal notebooks from nineteenth-century Central Asia, the manuscript NLR PNS 561 (National Library of Russia, Persian – New Series), kept at Saint Petersburg, occupies a special position. It is a multilayered manuscript with two main layers from the 1870s and the 1920s–1930s, respectively. In the second layer in particular, the manuscript is both a multi-script and a multi-graphic artifact. Some parts of this layer are quite likely autographs of a leading Bukharan intellectual, Abdarrauf Fitrat (1885–1938). This paper is a detailed description of the manuscript that also assesses the ascription of discrete manuscript sections to Fitrat as autographs.