We propose a physical scheme for the realization of two-dimensional topological odd-parity superfluidity in a spin-independent bond-centered square optical lattice based upon interband fermion pairing. The D4 point-group symmetry of the lattice protects a quadratic band crossing, which allows one to prepare a Fermi surface of spin-up fermions with odd parity close to the degeneracy point. In the presence of spin-down fermions with even parity populating a different energetically well-separated band, odd-parity pairing is favored. Strikingly, as a necessary prerequisite for pairing, both Fermi surfaces can be tuned to match well. As a result, topological superfluid phases emerge in the presence of merely s-wave interaction. Due to the Z2 symmetry of these odd-parity superfluids, we infer their topological features simply from the symmetry and the Fermi-surface topology as confirmed numerically.