DI- UND TRIPHOSPHAT-PROPHARMAKA

Link:
Autor/in:
Erscheinungsjahr:
2017
Medientyp:
Text
Beschreibung:
  • The invention relates to compounds which can be used as prodrugs, in particular nucleoside diphosphate and triphosphate prodrugs, and to a method for producing said compounds. The aim of the invention is to provide improved di- and/or triphosphate prodrugs, in particular nucleotide or nucleotide analog prodrugs. This is achieved in one aspect by providing bioreversibly and asymmetrically masked di­and triphosphate compounds, in particular nucleoside diphosphate and nucleoside triphosphate compounds or the analogs thereof. The masking only occurs at the terminal phosphate, i.e. at the ß- or y­phosphate, whereas the masking of the internal phosphate is omitted.
Lizenz:
  • info:eu-repo/semantics/restrictedAccess
Quellsystem:
Forschungsinformationssystem der UHH

Interne Metadaten
Quelldatensatz
oai:www.edit.fis.uni-hamburg.de:publications/cde84e7b-54d5-4445-a4e7-a3f5f682c2a1