Fulfilling the need for reproducible Quantum Dots (QDs) with certain spectroscopic features, high stability and luminescence we have established synthetic routes for the production of CdSe core as well as CdSe/shell particles in a continuous flow (cf) system. Our method features the deviation between nucleation and growth in two different parts of the system to mimic the well-known and often-used hot injection method for the synthesis of nanoparticles in organic solvents.