Synthesis and structural characterization of a trispyrrole iron(II) complex K(dme)(4)[tpa(Mes)Fe] and application in nitrous oxide dependent coupling reactions
A new synthetic route to the trispyrrole iron(II) complex {K(dme)4[tpaMesFe]} was established starting from BOC-protected pyrrol via synthesis of the corresponding boronic acid, cross-coupling reaction, deprotection, triple Mannich reaction, a deprotonation and finally a salt metathesis. The complex was characterized and applied in iron-catalyzed coupling reactions. In more detail, with catalytic amounts of K(dme)4[tpaMesFe] the homo-coupling of aromatic Grignard reagents as well as the hetero-coupling of aromatic Grignard reagents were feasible. Noteworthy, to force the reaction nitrous oxide was added to realize yields up to 93% at mild reaction conditions.