Synthesis, characterization and biomedical activities of molybdenum complexes of tridentate Schiff base ligands. Crystal and molecular structure of [MoO2(L10)(DMSO)] and [MoO2(L11)(DMSO)]
The molybdenum complexes of different Schiff base ligands have drawn remarkable attention due to their different biological and analytical activities. Several molybdenum complexes of different Schiff base ligands, L-1 to L-11 derived from dithiocarbazate, have been synthesized by the reaction of the ligands with molybdenum(VI)acetylacetonate. The complexes were characterized on the basis of IR,H-1 NMR and electronic spectral analyses, along with elemental, magnetochemical and conductometric data. All the complexes are diamagnetic and non-electrolytes in DMF solution. The molecular structures of two complexes were confirmed by X-ray crystallographic studies. Antibacterial and antifungal characteristics of the concerned compounds were investigated against different gram-positive and Gram negative bacteria, and against fungi, respectively. Most of the complexes show good activity against fungi and bacteria; in some cases, the complexes were more active than the standard medications Nystatin and Ampicillin respectively. (C) 2016 Elsevier Ltd. All rights reserved.