The decline in Christian interest in the literary and philosophical traditions of Judaism and the growing attention accorded to Hellas and the Hellenistic ‘spirit’ have a curious and intriguing history in the modern era. Such changing attitudes have naturally also affected the (hi)story of Jewish–Greek studies. On the one hand Greek and Hellenistic culture experienced a revival both in Christianity and in Judaism, especially in the nineteenth century. On the other hand, the growing wave of anti-Judaism and then anti-Semitism led to more negative assessments of Jewish history. Christian interest in the nineteenth century focused on the Septuagint (and its stories), Philo and other aspects of Jewish antiquity of relevance to Christian scholarly and general interest, while only scant attention was paid to later Jewish literature or post-‘biblical’ Jewish–Greek studies. Yet, as I will try to show in this chapter, the field of Jewish–Greek studies had a hesitant but solid beginning in the nineteenth century, addressing most aspects of what currently interests scholars.I shall begin by focusing on the turning point in Christian interest in Judaeo-Greek studies in the eighteenth to nineteenth century. I shall then examine work in this area conducted by the movement of the Wissenschaft des Judentums in the nineteenth and the beginning of the twentieth century, ending with some suggestive conclusions.