In this paper a new approach to predict the particle damping using a frequency based substructuring approach is presented. With this linear approach the consideration of particle dampers (PD) is possible without modelling its complex dynamic behaviour in detail with e.g. the discrete element method. The frequency response of the particle system - as one substructure - is determined experimentally. Finally, with a hybrid frequency based assembly, using test (particle damper) and simulation (honeycomb sandwich panel) results, is used to determine the dynamic behaviour of the entire system. In the paper the influence of the particle mass, the position of the damper, different test set-ups and sandwich panels with different composite lay-ups are investigated and compared to test results.