Cryptotomography:reconstructing 3D fourier intensities from randomly oriented single-shot diffraction patterns

Link:

https://doi.org/10.1103/PhysRevLett.104.225501

Autor/in:

Erscheinungsjahr:

2010

Medientyp:

Text

Beschreibung:

We reconstructed the 3D Fourier intensity distribution of monodisperse prolate nanoparticles using single-shot 2D coherent diffraction patterns collected at DESY's FLASH facility when a bright, coherent, ultrafast x-ray pulse intercepted individual particles of random, unmeasured orientations. This first experimental demonstration of cryptotomography extended the expansion-maximization-compression framework to accommodate unmeasured fluctuations in photon fluence and loss of data due to saturation or background scatter. This work is an important step towards realizing single-shot diffraction imaging of single biomolecules. © 2010 The American Physical Society.

Lizenz:

info:eu-repo/semantics/closedAccess

Quellsystem:

Forschungsinformationssystem der UHH

Interne Metadaten

Quelldatensatz: oai:www.edit.fis.uni-hamburg.de:publications/03242235-306b-4aad-bac3-199233642bdc