This chapter introduces the concept of “communicative figurations” as an analytical tool for investigating mediatization with a special focus on changing human interaction. The concept of “communicative figurations” is used to develop a transmedial analysis of the changing communicative construction of mediatized cultures and societies. Foci of this approach are the communicative forms, media environments, actor constellations, and thematic framings of social entities, for example the mediatized family, mediatized organizations, or the mediatized field of religion. This makes it possible to investigate patterns of belongings, power, rules and segmentation within processes of mediatization. The arguments are as follows: First, the chapter outlines a general approach on how to reflect the interrelation between mediatization, interaction and communication. Based on this, the concept of communicative figurations is introduced. This is followed by a reflection of the empirical grounding of communicative figurations, and then a conclusion regarding the relevance of this concept for mediatization research that is oriented to questions of interaction and communication.