Entrepreneurial Education needs to be transformed. Our seminar called Transformational Sustainability Entrepreneurship aims at meeting this need by guiding students to become change agents for tackling the grand societal challenges of our time. In this chapter, we explain the five fundamental aspects in which this seminar is designed for students’ transformational learning experience. The seminar itself is divided into three phases: Understanding, Creative Thinking, and Pitching with an overarching reflection process. We introduce the concept, which we have been using for four years at two different universities, for others to apply and use in their own teaching activities.