When Very High Energy (VHE) gamma-rays (E>100 GeV) transverse low energy photon fields, the production of electron-positron pairs leads to the attenuation of the intrinsic gamma-ray flux. This phenomena is well know for VHE radiation from extragalactic sources, like e.g. blazars, interacting with the cosmic infrared background. In this contribution the absorption of VHE gamma-rays due to the interaction with localized low energy radiation fields, e.g. the Milky Way diffuse radiation field, cluster radiation fields and radiation fields in voids and filaments is discussed. While the photon field densities of these inhomogeneous radiation fields can be several orders of magnitude higher compared to the homogeneous background, the distances are in general shorter leading to an overall smaller effect. On the other hand, the detection of such an attenuation could be used to study the IR emission on different scales, measure the distance of galactic sources, or investigate particle physics phenomena beyond the standard model. It is investigated how forthcoming imaging air Cherenkov telescopes, like CTA, and wide angle Cherenkov arrays, like HiSCORE, with their improved sensitivities up to several hundred TeV will measure this absorption feature.