In the Industry 4.0 interface designs need to be adjusted to cognitive and sensorimotor abilities of humans in order to ensure a faultless and ergonomic human-machine interaction. The perception and processing of stimuli as well as the reactive motor planning and response of humans is essential for the exchange of information. Attention processes play an eminent role in both the processing of stimuli and the motor response. This chapter presents the current state of research regarding attention models for perception and motor control. Various attention theories agree that the execution of motor-cognitive tasks depends on the task setting and the task conditions (e.g., the complexity or sensory modality conditions). These findings should be actively integrated into design processes of interfaces for human-machine interaction to avoid negative consequences.