Diffusion literature in International Relations (IR) has mostly focused on explaining patterns of convergence among states and international organizations. While numerous studies have revealed that ideas, norms, institutions, and practices often vary as they diffuse, the perspective of those people who experience the diffusion of global agendas at the local level is still under-researched. The diffusion of the human security agenda is explored in this article with a focus on how it is perceived in different sociocultural contexts. The positive and negative roles that non-state actors play in building human security are also addressed in order to shed light on the opportunities they have to become more effective in promoting the human security agenda. I argue that when non-state actors focus on solution-oriented research, improve communication, and foster interactive and interdisciplinary practices with other members of civil society, they are in a better position to understand and promote people’s development and security in a holistic and sustainable fashion.