35 Einträge gefunden

1. Molecular analyses of 15,542 patients with suspected BCR-ABL1-negative myeloproliferative disorders allow to develop a stepwise diagnostic workflow.

   1. Schnittger, Susanne
   2. Bacher, Ulrike
   3. Eder, Christiane
   4. Dicker, Frank
   5. Alpermann, Tamara
   6. Grossmann, Vera
   7. Kohlmann, Alexander

   2012 - Forschungsinformationssystem des UKE - frei zugänglich
2. Prognoses of MDS subtypes RARS, RCMD and RCMD-RS are comparable but cytogenetics separates a subgroup with inferior clinical course.

   1. Bacher, Ulrike
   2. Kern, Wolfgang
   3. Alpermann, Tamara
   4. Schnittger, Susanne
   5. Haferlach, Claudia
   6. Haferlach, Torsten

   2012 - Forschungsinformationssystem des UKE
3. TET2 deletions are a recurrent but rare phenomenon in myeloid malignancies and are frequently accompanied by TET2 mutations on the remaining allele.

   1. Bacher, Ulrike
   2. Weissmann, Sandra
   3. Kohlmann, Alexander
   4. Schindela, Sonja
   5. Alpermann, Tamara
   6. Schnittger, Susanne
   7. Kern, Wolfgang

   2012 - Forschungsinformationssystem des UKE
4. Multilineage dysplasia does not influence prognosis in CEBPA-mutated AML, supporting the WHO proposal to classify these patients as a unique entity.

   1. Bacher, Ulrike
   2. Schnittger, Susanne
   3. Macijewski, Katja
   4. Grossmann, Vera
   5. Kohlmann, Alexander
   6. Alpermann, Tamara
   7. Kowarsch, Andreas

   2012 - Forschungsinformationssystem des UKE
5. Amount of bone marrow blasts is strongly correlated to NPM1 and FLT3-ITD mutation rate in AML with normal karyotype.

   1. Haferlach, Torsten
   2. Bacher, Ulrike
   3. Alpermann, Tamara
   4. Haferlach, Claudia
   5. Kern, Wolfgang
   6. Schnittger, Susanne

   2012 - Forschungsinformationssystem des UKE
6. Monoclonal B-cell lymphocytosis is closely related to chronic lymphocytic leukaemia and may be better classified as early-stage CLL.

   1. Kern, Wolfgang
   2. Bacher, Ulrike
   3. Haferlach, Claudia
   4. Dicker, Frank
   5. Alpermann, Tamara
   6. Schnittger, Susanne
   7. Haferlach, Torsten

   2012 - Forschungsinformationssystem des UKE
7. Development and validation of a real-time quantification assay to detect and monitor BRAFV600E mutations in hairy cell leukemia.

   1. Schnittger, Susanne
   2. Bacher, Ulrike
   3. Haferlach, Torsten
   4. Wendland, Nicole
   5. Ulke, Madlen
   6. Dicker, Frank
   7. Grossmann, Vera

   2012 - Forschungsinformationssystem des UKE
8. Frequency and prognostic impact of the aberrant CD8 expression in 5,523 patients with chronic lymphocytic leukemia.

   1. Kern, Wolfgang
   2. Bacher, Ulrike
   3. Haferlach, Claudia
   4. Alpermann, Tamara
   5. Dicker, Frank
   6. Schnittger, Susanne
   7. Haferlach, Torsten

   2012 - Forschungsinformationssystem des UKE
9. ETV6 rearrangements are recurrent in myeloid malignancies and are frequently associated with other genetic events.

   1. Haferlach, Claudia
   2. Bacher, Ulrike
   3. Schnittger, Susanne
   4. Alpermann, Tamara
   5. Zenger, Melanie
   6. Kern, Wolfgang
   7. Haferlach, Torsten

   2012 - Forschungsinformationssystem des UKE
10. A copy number repeat polymorphism in the transactivation domain of the CEPBA gene is possibly associated with a protective effect against acquired CEBPA mutations: an analysis in 1135 patients with AML and 187 healthy controls.

    1. Schnittger, Susanne
    2. Bacher, Ulrike
    3. Eder, Christiane
    4. Lohse, Peter
    5. Haferlach, Claudia
    6. Kern, Wolfgang
    7. Haferlach, Torsten

    2011 - Forschungsinformationssystem des UKE
11. Several lymphoma-specific genetic events in parallel can be found in mature B-cell neoplasms.

    1. Bacher, Ulrike
    2. Haferlach, Torsten
    3. Alpermann, Tamara
    4. Kern, Wolfgang
    5. Schnittger, Susanne
    6. Haferlach, Claudia

    2011 - Forschungsinformationssystem des UKE
12. CDKN1B, encoding the cyclin-dependent kinase inhibitor 1B (p27), is located in the minimally deleted region of 12p abnormalities in myeloid malignancies and its low expression is a favorable prognostic marker in acute myeloid leukemia.

    1. Haferlach, Claudia
    2. Bacher, Ulrike
    3. Kohlmann, Alexander
    4. Schindela, Sonja
    5. Alpermann, Tamara
    6. Kern, Wolfgang
    7. Schnittger, Susanne

    2011 - Forschungsinformationssystem des UKE - frei zugänglich
13. Clinical impact of FLT3 mutation load in acute promyelocytic leukemia with t(15;17)/PML-RARA.

    1. Schnittger, Susanne
    2. Bacher, Ulrike
    3. Haferlach, Claudia
    4. Kern, Wolfgang
    5. Alpermann, Tamara
    6. Haferlach, Torsten

    2011 - Forschungsinformationssystem des UKE - frei zugänglich
14. Subclones with the t(9;22)/BCR-ABL1 rearrangement occur in AML and seem to cooperate with distinct genetic alterations.

    1. Bacher, Ulrike
    2. Haferlach, Torsten
    3. Alpermann, Tamara
    4. Zenger, Melanie
    5. Hochhaus, Andreas
    6. Beelen, Dietrich W
    7. Uppenkamp, Michael

    2011 - Forschungsinformationssystem des UKE
15. Acute monoblastic/monocytic leukemia and chronic myelomonocytic leukemia share common immunophenotypic features but differ in the extent of aberrantly expressed antigens and amount of granulocytic cells.

    1. Kern, Wolfgang
    2. Bacher, Ulrike
    3. Haferlach, Claudia
    4. Schnittger, Susanne
    5. Haferlach, Torsten

    2011 - Forschungsinformationssystem des UKE
16. Comparison of genetic and clinical aspects in patients with acute myeloid leukemia and myelodysplastic syndromes all with more than 50% of bone marrow erythropoietic cells.

    1. Bacher, Ulrike
    2. Haferlach, Claudia
    3. Alpermann, Tamara
    4. Kern, Wolfgang
    5. Schnittger, Susanne
    6. Haferlach, Torsten

    2011 - Forschungsinformationssystem des UKE - frei zugänglich
17. Associations between imatinib resistance conferring mutations and Philadelphia positive clonal cytogenetic evolution in CML.

    1. Schnittger, Susanne
    2. Bacher, Ulrike
    3. Dicker, Frank
    4. Kern, Wolfgang
    5. Alpermann, Tamara
    6. Haferlach, Torsten
    7. Haferlach, Claudia

    2010 - Forschungsinformationssystem des UKE
18. Mutations of the TET2 and CBL genes: novel molecular markers in myeloid malignancies.

    1. Bacher, Ulrike
    2. Haferlach, Claudia
    3. Schnittger, Susanne
    4. Kohlmann, Alexander
    5. Kern, Wolfgang
    6. Haferlach, Torsten

    2010 - Forschungsinformationssystem des UKE
19. The role of multiparameter flow cytometry for disease monitoring in AML.

    1. Kern, Wolfgang
    2. Bacher, Ulrike
    3. Haferlach, Claudia
    4. Schnittger, Susanne
    5. Haferlach, Torsten

    2010 - Forschungsinformationssystem des UKE
20. Multilineage dysplasia (MLD) in acute myeloid leukemia (AML) correlates with MDS-related cytogenetic abnormalities and a prior history of MDS or MDS/MPN but has no independent prognostic relevance: a comparison of 408 cases classified as "AML not otherwise specified" (AML-NOS) or "AML with myelodysplasia-related changes" (AML-MRC).

    1. Miesner, Miriam
    2. Haferlach, Claudia
    3. Bacher, Ulrike
    4. Weiss, Tamara
    5. Macijewski, Katja
    6. Kohlmann, Alexander
    7. Klein, Hans-Ulrich

    2010 - Forschungsinformationssystem des UKE