38 Einträge gefunden

1. A conformational transition of the D'D3 domain primes von Willebrand factor for multimerization

   1. Gruber, Sophia
   2. Löf, Achim
   3. Hausch, Adina
   4. Kutzki, Fabian
   5. Jöhr, Res
   6. Obser, Tobias
   7. König, Gesa

   2022 - Forschungsinformationssystem des UKE - frei zugänglich
2. Platelet adhesion and aggregate formation controlled by immobilised and soluble VWF

   1. Schneider, Matthias F
   2. Fallah, Mohammad A
   3. Mess, Christian
   4. Obser, Tobias
   5. Schneppenheim, Reinhard
   6. Alexander-Katz, Alfredo
   7. Schneider, Stefan W

   2020 - Forschungsinformationssystem des UKE - frei zugänglich
3. Upshaw-Schulman syndrome-associated ADAMTS13 variants possess proteolytic activity at the surface of endothelial cells and in simulated circulation

   1. Letzer, Anton
   2. Lehmann, Katja
   3. Mess, Christian
   4. König, Gesa
   5. Obser, Tobias
   6. Peine, Sven
   7. Schneppenheim, Sonja

   2020 - Forschungsinformationssystem des UKE
4. Characterization of VWF gene conversions causing von Willebrand disease

   1. Ahmad, Firdos
   2. Kannan, Meganathan
   3. Obser, Tobias
   4. Budde, Ulrich
   5. Schneppenheim, Sonja
   6. Saxena, Renu
   7. Schneppenheim, Reinhard

   2019 - Forschungsinformationssystem des UKE
5. The von Willebrand factor Tyr2561 allele is a gain-of-function variant and a risk factor for early myocardial infarction

   1. Schneppenheim, Reinhard
   2. Hellermann, Natalie
   3. Brehm, Maria A
   4. Klemm, Ulrike
   5. Obser, Tobias
   6. Huck, Volker
   7. Schneider, Stefan W

   2019 - Forschungsinformationssystem des UKE
6. Alteration in GPIIb/IIIa Binding of VWD-Associated von Willebrand Factor Variants with C-Terminal Missense Mutations

   1. König, Gesa
   2. Obser, Tobias
   3. Marggraf, Olivier
   4. Schneppenheim, Sonja
   5. Budde, Ulrich
   6. Schneppenheim, Reinhard
   7. Brehm, Maria A

   2019 - Forschungsinformationssystem des UKE
7. Von Willebrand Factor Mediates Pneumococcal Aggregation and Adhesion in Blood Flow

   1. Jagau, Hilger
   2. Behrens, Ina-Kristin
   3. Lahme, Karen
   4. Lorz, Georgina
   5. Köster, Reinhard W
   6. Schneppenheim, Reinhard
   7. Obser, Tobias

   2019 - Forschungsinformationssystem des UKE - frei zugänglich
8. Structure and dynamics of the platelet integrin-binding C4 domain of von Willebrand factor

   1. Xu, Emma-Ruoqi
   2. von Bülow, Sören
   3. Chen, Po-Chia
   4. Lenting, Peter J
   5. Kolšek, Katra
   6. Aponte-Santamaría, Camilo
   7. Simon, Bernd

   2019 - Forschungsinformationssystem des UKE
9. Interaction of von Willebrand factor domains with collagen investigated by single molecule force spectroscopy

   1. Posch, Sandra
   2. Obser, Tobias
   3. König, Gesa
   4. Schneppenheim, Reinhard
   5. Tampé, Robert
   6. Hinterdorfer, Peter

   2018 - Forschungsinformationssystem des UKE
10. Genetic and Functional Characterization of ADAMTS13 Variants in a Patient Cohort with Upshaw-Schulman Syndrome Investigated in Germany

    1. Hassenpflug, Wolf Achim
    2. Obser, Tobias
    3. Bode, Julia
    4. Oyen, Florian
    5. Budde, Ulrich
    6. Schneppenheim, Sonja
    7. Schneppenheim, Reinhard

    2018 - Forschungsinformationssystem des UKE
11. Enhanced Local Disorder in a Clinically Elusive von Willebrand Factor Provokes High-Affinity Platelet Clumping

    1. Tischer, Alexander
    2. Machha, Venkata R
    3. Frontroth, Juan P
    4. Brehm, Maria A
    5. Obser, Tobias
    6. Schneppenheim, Reinhard
    7. Mayne, Leland

    2017 - Forschungsinformationssystem des UKE
12. Mutation G1629E Increases von Willebrand Factor Cleavage via a Cooperative Destabilization Mechanism

    1. Aponte-Santamaría, Camilo
    2. Lippok, Svenja
    3. Mittag, Judith J
    4. Obser, Tobias
    5. Schneppenheim, Reinhard
    6. Baldauf, Carsten
    7. Gräter, Frauke

    2017 - Forschungsinformationssystem des UKE
13. Shear-Induced Unfolding and Enzymatic Cleavage of Full-Length VWF Multimers

    1. Lippok, Svenja
    2. Radtke, Matthias
    3. Obser, Tobias
    4. Kleemeier, Lars
    5. Schneppenheim, Reinhard
    6. Budde, Ulrich
    7. Netz, Roland R

    2016 - Forschungsinformationssystem des UKE
14. Force sensing by the vascular protein von Willebrand factor is tuned by a strong intermonomer interaction

    1. Müller, Jochen P
    2. Mielke, Salomé
    3. Löf, Achim
    4. Obser, Tobias
    5. Beer, Christof
    6. Bruetzel, Linda K
    7. Pippig, Diana A

    2016 - Forschungsinformationssystem des UKE
15. pH-Dependent Interactions in Dimers Govern the Mechanics and Structure of von Willebrand Factor

    1. Müller, Jochen P
    2. Löf, Achim
    3. Mielke, Salomé
    4. Obser, Tobias
    5. Bruetzel, Linda K
    6. Vanderlinden, Willem
    7. Lipfert, Jan

    2016 - Forschungsinformationssystem des UKE
16. Force-sensitive autoinhibition of the von Willebrand factor mediated by inter-domain interactions

    1. Aponte-Santamaría , Camilo
    2. Huck, Volker
    3. Posch, Sandra
    4. Bronowska, AK
    5. Grässle, Sandra
    6. Brehm, Maria
    7. Obser, Tobias

    2015 - Forschungsinformationssystem des UKE
17. von Willebrand Factor Directly Interacts With DNA From Neutrophil Extracellular Traps

    1. Grässle, Sandra
    2. Huck, Volker
    3. Pappelbaum, Karin I
    4. Gorzelanny, Christian
    5. Aponte-Santamaría, Camilo
    6. Baldauf, Carsten
    7. Gräter, Frauke

    2014 - Forschungsinformationssystem des UKE
18. Platelet-free shear flow assay facilitates analysis of shear-dependent functions of VWF and ADAMTS13

    1. Kraus, Emma
    2. Kraus, Kristina
    3. Obser, Tobias
    4. Oyen, Florian
    5. Klemm, Ulrike
    6. Schneppenheim, Reinhard
    7. Brehm, Maria A

    2014 - Forschungsinformationssystem des UKE
19. Characterisation of the p.A1461D mutation causing von Willebrand disease type 2B with severe thrombocytopenia, circulating giant platelets, and defective α-granule secretion

    1. Langer, Florian
    2. Obser, Tobias
    3. Oyen, Florian
    4. Spath, Brigitte
    5. Holstein, Katharina
    6. Greinacher, Andreas
    7. White, James G

    2014 - Forschungsinformationssystem des UKE
20. Performance evaluation and multicentre study of a von Willebrand factor activity assay based on GPIb binding in the absence of ristocetin

    1. Patzke, Juergen
    2. Budde, Ulrich
    3. Huber, Andreas
    4. Méndez, Adriana
    5. Muth, Heidrun
    6. Obser, Tobias
    7. Peerschke, Ellinor

    2014 - Forschungsinformationssystem des UKE