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- Jücker, Manfred
- Ehm, Patrick 8
- Nelson, Nina 8
- Ewald, Florian 7
- Grottke, Astrid 6
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51 Einträge gefunden
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Leukemia-associated mutations in SHIP1 inhibit its enzymatic activity, interaction with the GM-CSF receptor and Grb2, and its ability to inactivate PI3K/AKT signaling.
- Brauer, Helena
- Strauss, Julia
- Wegner, Wiebke
- Müller-Tidow, Carsten
- Horstmann, Martin
- Jücker, Manfred
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Combined targeting of AKT and mTOR synergistically inhibits proliferation of hepatocellular carcinoma cells.
- Grabinski, Nicole
- Ewald, Florian
- Hofmann, Bianca T.
- Staufer, Katharina
- Schumacher, Udo
- Nashan, Björn
- Jücker, Manfred
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Posttranscriptional regulation of the p85α adapter subunit of phosphatidylinositol 3-kinase in human leukemia cells
2011 - Forschungsinformationssystem des UKE -
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Reduced proliferation of CD34(+) cells from patients with acute myeloid leukemia after gene transfer of INPP5D.
2009 - Forschungsinformationssystem des UKE -
Overexpression of the p85alpha regulatory subunit of phosphatidylinositol 3-kinase inhibits GM-CSF-dependent colony formation of CD34+ hematopoietic progenitor cells.
2008 - Forschungsinformationssystem des UKE -
Mutations in the catalytic subunit of class IA PI3K confer leukemogenic potential to hematopoietic cells.
2008 - Forschungsinformationssystem des UKE -
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