Human prostate cancer in a clinically relevant xenograft mouse model: identification of β(1,6)-branched oligosaccharides as a marker of tumor progression.

Link:
Autor/in:
Erscheinungsjahr:
2012
Medientyp:
Text
Schlagworte:
  • Adult
  • Animals
  • Humans
  • Male
  • Aged
  • Middle Aged
  • Adolescent
  • Young Adult
  • Child
  • Disease Progression
  • Disease Models, Animal
  • Mice
  • Mice, Inbred BALB C
  • Mice, Knockout
  • Cell Line, Tumor
  • Neoplasm Staging
  • Neoplasm Metastasis
  • Protein Binding
  • Nerve Tissue Proteins/metabolism
  • Transplantation, Heterologous
  • Tumor Markers, Biological/*metabolism
  • Prostatic Neoplasms/*metabolism/pathology
  • Lectins/metabolism
  • N-Acetylglucosaminyltransferases/metabolism
  • Oligosaccharides, Branched-Chain/*metabolism
  • Phytohemagglutinins/metabolism
  • Adult
  • Animals
  • Humans
  • Male
  • Aged
  • Middle Aged
  • Adolescent
  • Young Adult
  • Child
  • Disease Progression
  • Disease Models, Animal
  • Mice
  • Mice, Inbred BALB C
  • Mice, Knockout
  • Cell Line, Tumor
  • Neoplasm Staging
  • Neoplasm Metastasis
  • Protein Binding
  • Nerve Tissue Proteins/metabolism
  • Transplantation, Heterologous
  • Tumor Markers, Biological/*metabolism
  • Prostatic Neoplasms/*metabolism/pathology
  • Lectins/metabolism
  • N-Acetylglucosaminyltransferases/metabolism
  • Oligosaccharides, Branched-Chain/*metabolism
  • Phytohemagglutinins/metabolism
Beschreibung:
  • To establish xenograft mouse models of metastatic and nonmetastatic human prostate cancer and to apply these models to the search for aberrant glycosylation patterns associated with tumor progression in vivo and in patients.
  • To establish xenograft mouse models of metastatic and nonmetastatic human prostate cancer and to apply these models to the search for aberrant glycosylation patterns associated with tumor progression in vivo and in patients.
Lizenz:
  • info:eu-repo/semantics/restrictedAccess
Quellsystem:
Forschungsinformationssystem des UKE

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oai:pure.atira.dk:publications/6f635f3a-d53e-478b-86b7-6692634ff5f2