Population-based Correspondence Models for Respiratory Motion Estimation in the Presence of Interfraction Motion Variations

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Erscheinungsjahr:
2015
Medientyp:
Text
Beschreibung:
  • Many respiratory motion compensation approaches in radiation
    therapy of thoracic and abdominal tumors are guided by external
    breathing signals. Patient-specific correspondence models based on planning
    4D data are used to relate signal measurements to internal motion.
    The motion estimation accuracy of these models during a treatment fraction
    depends on the degree of inter-fraction motion variations. Here, we
    investigate whether motion estimation accuracy in the presence of interfraction
    motion variations can be improved by (sub)population models,
    which incorporate patient-specific motion information and motion data
    from selected additional patients. A sparse manifold clustering approach
    is integrated into a regression-based correspondence modeling framework
    for automated identification of subpopulations of patients with similar
    motion characteristics. In an evaluation with repeated 4D CT scans of 13
    patients, subpopulation models, on average, outperform patient-specific
    correspondence models in the presence of inter-fraction motion variations.
Lizenz:
  • info:eu-repo/semantics/restrictedAccess
Quellsystem:
Forschungsinformationssystem des UKE

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oai:pure.atira.dk:publications/e44900d8-dffd-4703-a33a-13b41c990be1