Advances in Manufacturing of Biodegradable Spinal Cord Implants on Microscale through Micromolding and 3D Printing

Link:
Autor/in:
Verlag/Körperschaft:
Hamburg University of Technology
Erscheinungsjahr:
2019
Medientyp:
Text
Schlagworte:
  • 3D Printing
  • Biodegradable
  • Implant
  • Micromolding
  • Poly(Lactic-co-Glycolic Acid)
  • Spinal Cord Injury
Beschreibung:
  • Spinal cord injury is a life changing event potentially leading to permanent paralysis. This paper presents advances in developing an implant for spinal cord treatment called mechanical microconnector system (mMS). A micromolding process was developed to transfer the mMS from biocompatible to biodegradable material. The results consist of a determined parameter-set for micromolding of biodegradable mMS for two poly(lactic-co-glycolic acid) (PLGA) compounds and polycaprolactone (PCL). The process starts with a complex 3D quartz glass premaster, built through ultrafast laser radiation and subsequent wet-chemical etching (SLE = selective laser induced etching). The incorporation of a 3D printing technique arises from the objective to individualize and automatically produce biodegradable implants out of medical image data in future.
Beziehungen:
DOI 10.1109/TRANSDUCERS.2019.8808647
Quellsystem:
TUHH Open Research

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oai:tore.tuhh.de:11420/3371