No association between transmembrane protein-tyrosine phosphatase receptor type C (PTPRC) exon A 77C>G transversion and liver transplant rejection.

Link:
Autor/in:
Erscheinungsjahr:
2012
Medientyp:
Text
Schlagworte:
  • Adult
  • Humans
  • Male
  • Aged
  • Female
  • Middle Aged
  • Genotype
  • Gene Frequency
  • Graft Survival
  • European Continental Ancestry Group/genetics
  • *Genetic Predisposition to Disease
  • Antigens, CD45/*genetics
  • Cytosine/metabolism
  • *Exons
  • Genetic Association Studies/methods
  • Graft Rejection/*genetics/metabolism
  • Guanine/metabolism
  • Liver Transplantation/adverse effects/*pathology
  • Adult
  • Humans
  • Male
  • Aged
  • Female
  • Middle Aged
  • Genotype
  • Gene Frequency
  • Graft Survival
  • European Continental Ancestry Group/genetics
  • *Genetic Predisposition to Disease
  • Antigens, CD45/*genetics
  • Cytosine/metabolism
  • *Exons
  • Genetic Association Studies/methods
  • Graft Rejection/*genetics/metabolism
  • Guanine/metabolism
  • Liver Transplantation/adverse effects/*pathology
Beschreibung:
  • This study was carried out to evaluate the association between 77C>G transversion (rs17612648) in exon A of the PTPRC gene and liver transplant rejection. No significant differences in genotype and allele frequencies of the 77C>G transversion were detected between recipients without rejection (n = 106) and recipients with rejection (n = 104). In conclusion, there was no evidence for the contribution of the 77C>G transversion in susceptibility to liver transplant rejection in a Caucasian population.
  • This study was carried out to evaluate the association between 77C>G transversion (rs17612648) in exon A of the PTPRC gene and liver transplant rejection. No significant differences in genotype and allele frequencies of the 77C>G transversion were detected between recipients without rejection (n = 106) and recipients with rejection (n = 104). In conclusion, there was no evidence for the contribution of the 77C>G transversion in susceptibility to liver transplant rejection in a Caucasian population.
Lizenz:
  • info:eu-repo/semantics/restrictedAccess
Quellsystem:
Forschungsinformationssystem des UKE

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Quelldatensatz
oai:pure.atira.dk:publications/370cb922-3b51-4074-a96f-c14016f63fab