Pharmacokinetics of meropenem during advanced organ support (ADVOS®) and continuous renal replacement therapy
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- Erscheinungsjahr:
- 2021
- Medientyp:
- Text
- Beschreibung:
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The advanced organ support (ADVOS) system allows to eliminate water-soluble as well as protein-bound molecules. Despite its clinical features, to date nothing is known about the elimination of clinically relevant drugs such as antiinfectives. Therefore, we report a case treated with ADVOS, continuous renal replacement therapy (CRRT), and meropenem (1 g 8-hourly) for empiric sepsis therapy monitored by meropenem drug levels. ADVOS showed more efficient elimination of meropenem compared to CRRT which has to be considered when evaluating dosing regimens.
- Lizenz:
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- info:eu-repo/semantics/closedAccess
- Quellsystem:
- Forschungsinformationssystem des UKE
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- Quelldatensatz
- oai:pure.atira.dk:publications/14049582-01cb-4cc4-a657-1311d2732ee0