B-1252: The impact of [68Ga]PSMA I&T PET/CT on radiotherapy planning in patients with biochemical cancer relapse after radical prostatectomy in prostate cancer.

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Erscheinungsjahr:
2018
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  • Purpose: To determine the impact of [68Ga]PSMA I&T PET/CT on radiotherapy planning of biochemical cancer relapse of prostate cancer. Methods and Materials: We performed a retrospective analysis of 75 patients who underwent [68Ga]PSMA I&T PET/CT scans prior to scheduled radiotherapy treatment. All patients had a documented biochemical relapse after radical prostatectomy. The age distribution was median 69 (range 52-86) years. The PSA level was median 0.2 (range 0.02-653.2) ng/ml. We compared the impact of [68Ga]PSMA I&T PET/CT on lesion detection and treatment decision. Results: [68Ga]PSMA I&T PET/CT revealed a total of 47 positive lesions, whereas CT detected 18 lesions. The therapeutic regimen was changed in 32 of 75 cases (43%) based on the [68Ga]PSMA I&T PET/CT. In 31 cases (41%) it upstaged to an enhanced tumour extension. Twenty-five cases (33%) received an additional boost to the [68Ga]PSMA I&T PET/CT-positive findings. Conclusion: [68Ga]PSMA I&T PET/CT is an advanced hybrid imaging technique prior radiotherapy treatment for prostate cancer patients with proven biochemical relapse. It is significantly impacting the radiother
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  • info:eu-repo/semantics/restrictedAccess
Quellsystem:
Forschungsinformationssystem des UKE

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oai:pure.atira.dk:publications/e5d5aa85-ea8d-40ff-9268-7ae47ffd498e