No effect of the transforming growth factor β1 promoter polymorphism C-509T on TGFB1 gene expression, protein secretion, or cellular radiosensitivity.

Link:
Autor/in:
Erscheinungsjahr:
2013
Medientyp:
Text
Schlagworte:
  • Humans
  • Male
  • Female
  • Genotype
  • Reverse Transcriptase Polymerase Chain Reaction
  • Protein Array Analysis/methods
  • Colony-Forming Units Assay
  • Polymorphism, Single Nucleotide/*physiology
  • Promoter Regions, Genetic/*physiology
  • Radiation Tolerance/*genetics
  • Transforming Growth Factor beta1/*genetics/*metabolism
  • Breast Neoplasms
  • Fibroblasts/metabolism/radiation effects
  • Gene Expression Regulation/*genetics/radiation effects
  • Lymphocytes/metabolism/radiation effects
  • Twins, Monozygotic
  • Humans
  • Male
  • Female
  • Genotype
  • Reverse Transcriptase Polymerase Chain Reaction
  • Protein Array Analysis/methods
  • Colony-Forming Units Assay
  • Polymorphism, Single Nucleotide/*physiology
  • Promoter Regions, Genetic/*physiology
  • Radiation Tolerance/*genetics
  • Transforming Growth Factor beta1/*genetics/*metabolism
  • Breast Neoplasms
  • Fibroblasts/metabolism/radiation effects
  • Gene Expression Regulation/*genetics/radiation effects
  • Lymphocytes/metabolism/radiation effects
  • Twins, Monozygotic
Beschreibung:
  • To study whether the promoter polymorphism (C-509T) affects transforming growth factor ?1 gene (TGFB1) expression, protein secretion, and/or cellular radiosensitivity for both human lymphocytes and fibroblasts.
  • To study whether the promoter polymorphism (C-509T) affects transforming growth factor ?1 gene (TGFB1) expression, protein secretion, and/or cellular radiosensitivity for both human lymphocytes and fibroblasts.
Lizenz:
  • info:eu-repo/semantics/restrictedAccess
Quellsystem:
Forschungsinformationssystem des UKE
Interne Metadaten
Quelldatensatz
oai:pure.atira.dk:publications/be78fa5d-8c61-42c1-b07f-c97a4db12964