Role of panendoscopy in identifying and managing risk of head and neck squamous cell carcinoma in routine follow-up: a retrospective clinical evaluation
- Link:
- Autor/in:
- Erscheinungsjahr:
- 2015
- Medientyp:
- Text
- Schlagworte:
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- dk/atira/pure/publikationen_lom_relevant/cancer
- Cancer Medicine – University Cancer Center Hamburg (UCCH)
- Aged
- Carcinoma, Squamous Cell
- Disease Management
- Endoscopy
- Female
- Follow-Up Studies
- Germany
- Head and Neck Neoplasms
- Humans
- Incidence
- Male
- Middle Aged
- Neoplasm Recurrence, Local
- Neoplasm Staging
- Positron-Emission Tomography
- Predictive Value of Tests
- Prognosis
- Retrospective Studies
- Sensitivity and Specificity
- Tomography, X-Ray Computed
- dk/atira/pure/keywords/workgroup/143
- AG Statistische Beratung (143)
- Beschreibung:
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We discuss the clinical effectiveness and predictive value of routine panendoscopy for surveillance and follow-up of head and neck squamous cell carcinoma (HNSCC). Retrospective comparative study. Department of Otolaryngology-Head and Neck Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. Two hundred and four HNSCC patients (follow-up between 2004 and 2007) were retrospectively evaluated. During follow-up, panendoscopy was performed routinely once a year. To avoid unnecessary procedures, we evaluated the value of radiological and clinical parameters in follow-up. On comparing normal-computerized tomography (CT) vs. abnormal CT results, a 13-fold higher frequency of recurrence (odds ratio 12.74; 95% CI 4.22, 38.48; p < 0.001) was found. Additionally, patient medical history, clinical investigation, and recurrence pattern were significant parameters when detecting a possible recurrence. Panendoscopy could have been avoided in 40% of patients with HNSCC (173/432). A follow-up schedule avoiding routine panendoscopy in HNSCC follow-up when the combination of diagnostic parameters is satisfactory does not influence the sensitivity or specificity of the test.
- Lizenz:
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- info:eu-repo/semantics/restrictedAccess
- Quellsystem:
- Forschungsinformationssystem des UKE
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- Quelldatensatz
- oai:pure.atira.dk:publications/8a564dee-dc0d-4f0c-b2e5-fde60f986310