Synthetic pathways and processes for effective production of 5-hydroxytryptophan and serotonin from glucose in Escherichia coli

Link:
Autor/in:
Verlag/Körperschaft:
Hamburg University of Technology
Erscheinungsjahr:
2018
Medientyp:
Text
Schlagworte:
  • 5-hydroxytryptophan
  • Aromatic amino acid hydroxylase
  • Protein engineering
  • Serotonin
  • Synthetic pathway
  • 570: Biowissenschaften, Biologie
  • 620: Ingenieurwissenschaften
  • 570
  • 620
Beschreibung:
  • Tryptophan derivatives such as 5-hydroxytryptophan (5HTP) and serotonin are valuable molecules with pharmaceutical interest. 5HTP is presently mainly obtained by extraction from the plant Griffonia simplicifolia and serotonin is produced by chemical synthesis. A simple biotechnological method for the production of these compounds is desired.
Beziehungen:
DOI 10.1186/s13036-018-0094-7
Lizenzen:
  • info:eu-repo/semantics/openAccess
  • https://creativecommons.org/licenses/by/4.0/
Quellsystem:
TUHH Open Research
Interne Metadaten
Quelldatensatz
oai:tore.tuhh.de:11420/2206