49 Einträge gefunden

1. School of cheminformatics in Latin America

   1. Gonzalez-Ponce, Karla
   2. Horta Andrade, Carolina
   3. Hunter, Fiona
   4. Kirchmair, Johannes
   5. Martinez-Mayorga, Karina
   6. Medina-Franco, José L.
   7. Rarey, Matthias

   2023 - Forschungsinformationssystem der UHH - frei zugänglich
2. Reduced expression and activity of patient-derived SHIP1 phosphatase domain mutants

   1. Ehm, Patrick
   2. Nelson, Nina
   3. Giehler, Susanne
   4. Schaks, Matthias
   5. Bettin, Bettina
   6. Kirchmair, Johannes
   7. Jücker, Manfred

   2023 - Forschungsinformationssystem des UKE
3. G392E neuroserpin causing the dementia FENIB is secreted from cells but is not synaptotoxic

   1. Ingwersen, Thies
   2. Linneberg, Christian
   3. D'Acunto, Emanuela
   4. Temori, Shabnam
   5. Paolucci, Irene
   6. Wasilewski, David
   7. Mohammadi, Behnam

   2021 - Forschungsinformationssystem des UKE - frei zugänglich
4. Cypstrate: A set of machine learning models for the accurate classification of cytochrome p450 enzyme substratesand non-substrates

   1. Holmer, Malte
   2. de Bruyn Kops, Christina
   3. Stork, Conrad
   4. Kirchmair, Johannes

   2021 - Forschungsinformationssystem der UHH - frei zugänglich
5. AKT1 and PTEN show the highest affinities among phosphoinositide binding proteins for the second messengers PtdIns(3,4,5)P3 and PtdIns(3,4)P2

   1. Nelson, Nina
   2. Razeto, Adelia
   3. Gilardi, Alessia
   4. Grättinger, Mira
   5. Kirchmair, Johannes
   6. Jücker, Manfred

   2021 - Forschungsinformationssystem des UKE
6. Skin Doctor CP: Conformal Prediction of the Skin Sensitization Potential of Small Organic Molecules

   1. Wilm, A.
   2. Norinder, U.
   3. Agea, M.I.
   4. De Bruyn Kops, C.
   5. Stork, C.
   6. Kühnl, J.
   7. Kirchmair, Johannes

   2021 - Forschungsinformationssystem der UHH - frei zugänglich
7. GLORYx: Prediction of the Metabolites Resulting from Phase 1 and Phase 2 Biotransformations of Xenobiotics

   1. De Bruyn Kops, Christina
   2. Šícho, Martin
   3. Mazzolari, Angelica
   4. Kirchmair, Johannes

   2021 - Forschungsinformationssystem der UHH - frei zugänglich
8. Antibacterial activity of xylose-derived LpxC inhibitors – Synthesis, biological evaluation and molecular docking studies

   1. Dreger, A.
   2. Hoff, K.
   3. Agoglitta, O.
   4. Hotop, S.-K.
   5. Brönstrup, M.
   6. Heisig, P.
   7. Kirchmair, Johannes

   2021 - Forschungsinformationssystem der UHH
9. Mechanism of BIP-4 mediated inhibition of InsP3Kinase-A

   1. Paraschiakos, Themistoklis
   2. Flat, Wilhelm
   3. Chen, Ya
   4. Kirchmair, Johannes
   5. Windhorst, Sabine

   2021 - Forschungsinformationssystem des UKE - frei zugänglich
10. Validation strategies for target prediction methods

    1. Mathai, N.
    2. Chen, Y.
    3. Kirchmair, Johannes

    2020 - Forschungsinformationssystem der UHH
11. Natural products against acute respiratory infections: Strategies and lessons learned

    1. Langeder, Julia
    2. Grienke, Ulrike
    3. Chen, Ya
    4. Kirchmair, Johannes
    5. Schmidtke, Michaela
    6. Rollinger, Judith M.

    2020 - Forschungsinformationssystem der UHH
12. HDAC3i‐Finder: A Machine Learning‐based Computational Tool to Screen for HDAC3 Inhibitors

    1. Li, Shan
    2. Ding, Yu
    3. Chen, Miaomiao
    4. Chen, Ya
    5. Kirchmair, Johannes
    6. Zhu, Zihao
    7. Wu, Song

    2020 - Forschungsinformationssystem der UHH
13. Scope of 3D Shape-Based Approaches in Predicting the Macromolecular Targets of Structurally Complex Small Molecules including Natural Products and Macrocyclic Ligands

    1. Chen, Y.
    2. Mathai, N.
    3. Kirchmair, Johannes
    4. Kirchmair, Johannes
    5. Kirchmair, Johannes

    2020 - Forschungsinformationssystem der UHH
14. ALADDIN: Docking Approach Augmented by Machine Learning for Protein Structure Selection Yields Superior Virtual Screening Performance

    1. Fan, N.
    2. Bauer, C.A.
    3. Stork, C.
    4. de Bruyn Kops, C.
    5. Kirchmair, Johannes

    2020 - Forschungsinformationssystem der UHH - frei zugänglich
15. N-thiadiazole-4-hydroxy-2-quinolone-3-carboxamides bearing heteroaromatic rings as novel antibacterial agents: Design, synthesis, biological evaluation and target identification

    1. Xue, W.
    2. Li, X.
    3. Ma, G.
    4. Zhang, H.
    5. Chen, Y.
    6. Kirchmair, Johannes
    7. Xia, J.

    2020 - Forschungsinformationssystem der UHH
16. Cheminformatics in Natural Product-based Drug Discovery

    1. Chen, Y.
    2. Kirchmair, Johannes

    2020 - Forschungsinformationssystem der UHH
17. NERDD: A web portal providing access to in silico tools for drug discovery

    1. Stork, C.
    2. Embruch, G.
    3. Šícho, M.
    4. De Bruyn Kops, C.
    5. Chen, Y.
    6. Svozil, D.
    7. Kirchmair, Johannes

    2020 - Forschungsinformationssystem der UHH - frei zugänglich
18. Conformator: A Novel Method for the Generation of Conformer Ensembles

    1. Friedrich, Nils Ole
    2. Flachsenberg, Florian
    3. Meyder, Agnes
    4. Sommer, Kai
    5. Kirchmair, Johannes
    6. Rarey, Matthias

    2019 - Forschungsinformationssystem der UHH
19. Analysis of the FLVR motif of SHIP1 and its importance for the protein stability of SH2 containing signaling proteins

    1. Ehm, Patrick A H
    2. Lange, Fabiola
    3. Hentschel, Carolin
    4. Jepsen, Anneke
    5. Glück, Madeleine
    6. Nelson, Nina
    7. Bettin, Bettina

    2019 - Forschungsinformationssystem des UKE
20. Analysis of the FLVR motif of SHIP1 and its importance for the protein stability of SH2 containing signaling proteins

    1. Ehm, Patrick A.H.
    2. Lange, Fabiola
    3. Hentschel, Carolin
    4. Jepsen, Anneke
    5. Glück, Madeleine
    6. Nelson, Nina
    7. Bettin, Bettina

    2019 - Forschungsinformationssystem der UHH