20 Einträge gefunden

1. Translational investigation of electrophysiology in hypertrophic cardiomyopathy

   1. Flenner, Frederik
   2. Jungen, Christiane
   3. Küpker, Nadine
   4. Ibel, Antonia
   5. Kruse, Martin
   6. Koivumäki, Jussi T
   7. Rinas, Anna

   2021 - Forschungsinformationssystem des UKE - frei zugänglich
2. Ouabain worsens diastolic sarcomere length in myocytes from a cardiomyopathy mouse model

   1. Düsener, Silke
   2. Flenner, Frederik
   3. Maack, Christoph
   4. Kohlhaas, Michael
   5. Bay, Johannes
   6. Carrier, Lucie
   7. Friedrich, Felix W

   2021 - Forschungsinformationssystem des UKE
3. Impairment of the ER/mitochondria compartment in human cardiomyocytes with PLN p.Arg14del mutation

   1. Cuello, Friederike
   2. Knaust, Anika E
   3. Saleem, Umber
   4. Loos, Malte
   5. Raabe, Janice
   6. Mosqueira, Diogo
   7. Laufer, Sandra

   2021 - Forschungsinformationssystem des UKE - frei zugänglich
4. Analysis of Contractile Function of Permeabilized Human Hypertrophic Cardiomyopathy Multicellular Heart Tissue

   1. Kresin, Nico
   2. Stücker, Sabrina
   3. Krämer, Elisabeth
   4. Flenner, Frederik
   5. Mearini, Giulia
   6. Münch, Julia
   7. Patten, Monica

   2019 - Forschungsinformationssystem des UKE - frei zugänglich
5. Increased arrhythmia susceptibility in type 2 diabetic mice related to dysregulation of ventricular sympathetic innervation

   1. Jungen, Christiane
   2. Scherschel, Katharina
   3. Flenner, Frederik
   4. Jee, Haesung
   5. Rajendran, Pradeep
   6. De Jong, Kirstie A
   7. Nikolaev, Viacheslav

   2019 - Forschungsinformationssystem des UKE
6. In Vitro Negative Inotropic Effect of Low Concentrations of Bupivacaine Relates to Diminished Ca2+ Sensitivity but not to Ca2+ Handling or β-Adrenoceptor Signaling

   1. Flenner, Frederik
   2. Arlt, Nicole
   3. Nasib, Mahtab
   4. Schobesberger, Sophie
   5. Koch, Thea
   6. Ravens, Ursula
   7. Friedrich, Felix

   2018 - Forschungsinformationssystem des UKE
7. Low Resting Membrane Potential and Low Inward Rectifier Potassium Currents Are Not Inherent Features of hiPSC-Derived Cardiomyocytes

   1. Horváth, András
   2. Lemoine, Marc D
   3. Löser, Alexandra
   4. Mannhardt, Ingra
   5. Flenner, Frederik
   6. Uzun, Ahmet Umur
   7. Neuber, Christiane

   2018 - Forschungsinformationssystem des UKE - frei zugänglich
8. Atrial-like Engineered Heart Tissue: An In Vitro Model of the Human Atrium

   1. Lemme, Marta
   2. Ulmer, Bärbel M
   3. Lemoine, Marc D
   4. Zech, Antonia T L
   5. Flenner, Frederik
   6. Ravens, Ursula
   7. Reichenspurner, Hermann

   2018 - Forschungsinformationssystem des UKE - frei zugänglich
9. Human iPSC-derived cardiomyocytes cultured in 3D engineered heart tissue show physiological upstroke velocity and sodium current density

   1. Lemoine, Marc D
   2. Mannhardt, Ingra
   3. Breckwoldt, Kaja
   4. Prondzynski, Maksymilian
   5. Flenner, Frederik
   6. Ulmer, Bärbel
   7. Hirt, Marc N

   2017 - Forschungsinformationssystem des UKE - frei zugänglich
10. Blinded contractility analysis in hiPSC-cardiomyocytes in engineered heart tissue format: Comparison with human atrial trabeculae

    1. Mannhardt, Ingra
    2. Eder, Alexandra
    3. Dumotier, Berengere
    4. Prondzynski, Maksymilian
    5. Krämer, Elisabeth
    6. Traebert, Martin
    7. Söhren, Klaus-Dieter

    2017 - Forschungsinformationssystem des UKE
11. Diltiazem prevents stress-induced contractile deficits in cardiomyocytes, but does not reverse the cardiomyopathy phenotype in Mybpc3-knock-in mice

    1. Flenner, Frederik
    2. Geertz, Birgit
    3. Reischmann, Silke
    4. Weinberger, Florian
    5. Eschenhagen, Thomas
    6. Carrier, Lucie
    7. Friedrich, Felix

    2017 - Forschungsinformationssystem des UKE - frei zugänglich
12. Evaluation of MYBPC3 trans-Splicing and Gene Replacement as Therapeutic Options in Human iPSC-Derived Cardiomyocytes

    1. Prondzynski, Maksymilian
    2. Krämer, Elisabeth
    3. Laufer, Sandra
    4. Domke-Shibamiya, Aya
    5. Pless, Ole
    6. Flenner, Frederik
    7. Müller, Oliver J

    2017 - Forschungsinformationssystem des UKE - frei zugänglich
13. Epigallocatechin-3-gallate accelerates relaxation and Ca²⁺ transient decay and desensitizes myofilaments in healthy and cardiomyopathic Mybpc3-targeted knock-in mice

    1. Friedrich, Felix
    2. Flenner, Frederik
    3. Nasib, Mahtab
    4. Eschenhagen, Thomas
    5. Carrier, Lucie

    2016 - Forschungsinformationssystem des UKE - frei zugänglich
14. Ranolazine antagonizes catecholamine-induced dysfunction in isolated cardiomyocytes, but lacks long-term therapeutic effects in vivo in a mouse model of hypertrophic cardiomyopathy

    1. Flenner, Frederik
    2. Friedrich, Felix W
    3. Ungeheuer, Nele
    4. Christ, Torsten
    5. Geertz, Birgit
    6. Reischmann, Silke
    7. Wagner, Stefan

    2016 - Forschungsinformationssystem des UKE
15. β 1 Adrenoceptor antagonistic effects of the supposedly selective β 2 adrenoceptor antagonist ICI 118,551 on the positive inotropic effect of adrenaline in murine hearts

    1. Pecha, Simon
    2. Flenner, Frederik
    3. Söhren, Klaus-Dieter
    4. Lorenz, Kristina
    5. Eschenhagen, Thomas
    6. Christ, Torsten

    2015 - Forschungsinformationssystem des UKE - frei zugänglich
16. Evaluation of drug therapies targeting calcium homeostasis in a mouse model of hypertrophic cardiomyopathy

    1. Flenner, Frederik

    2015 - Forschungsinformationssystem der UHH - frei zugänglich
17. I-1-deficiency negatively impacts survival in a cardiomyopathy mouse model

    1. Friedrich, Felix
    2. Sotoud, Hannieh
    3. Geertz, Birgit
    4. Weber, Silvio
    5. Flenner, Frederik
    6. Reischmann, Silke
    7. Eschenhagen, Thomas

    2015 - Forschungsinformationssystem des UKE - frei zugänglich
18. Evaluation of drug therapies targeting calcium homeostasis in a mouse model of hypertrophic cardiomyopathy, Evaluation von auf die Kalziumhomöostase gerichteten pharmakologischen Therapien in einem Mausmodell der hypertrophen Kardiomyopathie

    1. Flenner, Frederik

    2015 - E-Dissertationen der UHH - frei zugänglich
19. Automated analysis of contractile force and Ca2+ transients in engineered heart tissue

    1. Stoehr, Andrea
    2. Neuber, Christiane
    3. Baldauf, Christina
    4. Vollert, Ingra
    5. Friedrich, Felix W
    6. Flenner, Frederik
    7. Carrier, Lucie

    2014 - Forschungsinformationssystem des UKE
20. Contractile abnormalities and altered drug response in engineered heart tissue from Mybpc3-targeted knock-in mice

    1. Stöhr, Andrea
    2. Friedrich, Felix W
    3. Flenner, Frederik
    4. Geertz, Birgit
    5. Eder, Alexandra
    6. Schaaf, Sebastian
    7. Hirt, Marc N

    2013 - Forschungsinformationssystem des UKE