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22 Einträge gefunden

Establishment of a Transformation Coupled in vitro End Joining Assay to Estimate Radiosensitivity in Tumor Cells
2020 - Forschungsinformationssystem des UKE
BCL2-overexpressing prostate cancer cells rely on PARP1-dependent end-joining and are sensitive to combined PARP inhibitor and radiation therapy
2018 - Forschungsinformationssystem des UKE
Impaired 53BP1/RIF1 DSB mediated end-protection stimulates CtIP-dependent end resection and switches the repair to PARP1-dependent end joining in G1
2016 - Forschungsinformationssystem des UKE
DNA repair after oncological therapy (radiotherapy and chemotherapy)
2016 - Forschungsinformationssystem des UKE
Sorafenib inhibits cell growth but fails to enhance radio- and chemosensitivity of glioblastoma cell lines
2016 - Forschungsinformationssystem des UKE
Association between SNPs in defined functional pathways and risk of early or late toxicity as well as individual radiosensitivity
2015 - Forschungsinformationssystem des UKE
EGFRvIII does not affect radiosensitivity with or without gefitinib treatment in glioblastoma cells
2015 - Forschungsinformationssystem des UKE
Quantitative proteomics unveiled: Regulation of DNA double strand break repair by EGFR involves PARP1
2015 - Forschungsinformationssystem des UKE
The inhibition of PARP but not EGFR results in the radiosensitization of HPV/p16-positive HNSCC cell lines
2014 - Forschungsinformationssystem des UKE
Inhibition of PARP1-dependent end-joining contributes to Olaparib-mediated radiosensitization in tumor cells
2014 - Forschungsinformationssystem des UKE - frei zugänglich
RAD51 overexpression is a negative prognostic marker for colorectal adenocarcinoma
2013 - Forschungsinformationssystem des UKE
HPV-positive HNSCC cell lines but not primary human fibroblasts are radiosensitized by the inhibition of Chk1
2013 - Forschungsinformationssystem des UKE
HNSCC cell lines positive for HPV and p16 possess higher cellular radiosensitivity due to an impaired DSB repair capacity.
2013 - Forschungsinformationssystem des UKE
No effect of the transforming growth factor β1 promoter polymorphism C-509T on TGFB1 gene expression, protein secretion, or cellular radiosensitivity.
2013 - Forschungsinformationssystem des UKE
p53 modulates homologous recombination at I-SceI-induced double-strand breaks through cell-cycle regulation.
2013 - Forschungsinformationssystem des UKE
The absence of Ku but not defects in classical non-homologous end-joining is required to trigger PARP1-dependent end-joining
2013 - Forschungsinformationssystem des UKE
Sorafenib sensitizes head and neck squamous cell carcinoma cells to ionizing radiation
2013 - Forschungsinformationssystem des UKE
DNA damage by X-rays and their impact on replication processes.
2012 - Forschungsinformationssystem des UKE
Association of single nucleotide polymorphisms in the genes ATM, GSTP1, SOD2, TGFB1, XPD and XRCC1 with risk of severe erythema after breast conserving radiotherapy.
2012 - Forschungsinformationssystem des UKE - frei zugänglich
In tumor cells regulation of DNA double strand break repair through EGF receptor involves both NHEJ and HR and is independent of p53 and K-Ras status.
2011 - Forschungsinformationssystem des UKE

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Establishment of a Transformation Coupled in vitro End Joining Assay to Estimate Radiosensitivity in Tumor Cells

BCL2-overexpressing prostate cancer cells rely on PARP1-dependent end-joining and are sensitive to combined PARP inhibitor and radiation therapy

Impaired 53BP1/RIF1 DSB mediated end-protection stimulates CtIP-dependent end resection and switches the repair to PARP1-dependent end joining in G1

DNA repair after oncological therapy (radiotherapy and chemotherapy)

Sorafenib inhibits cell growth but fails to enhance radio- and chemosensitivity of glioblastoma cell lines

Association between SNPs in defined functional pathways and risk of early or late toxicity as well as individual radiosensitivity

EGFRvIII does not affect radiosensitivity with or without gefitinib treatment in glioblastoma cells

Quantitative proteomics unveiled: Regulation of DNA double strand break repair by EGFR involves PARP1

The inhibition of PARP but not EGFR results in the radiosensitization of HPV/p16-positive HNSCC cell lines

Inhibition of PARP1-dependent end-joining contributes to Olaparib-mediated radiosensitization in tumor cells

RAD51 overexpression is a negative prognostic marker for colorectal adenocarcinoma

HPV-positive HNSCC cell lines but not primary human fibroblasts are radiosensitized by the inhibition of Chk1

HNSCC cell lines positive for HPV and p16 possess higher cellular radiosensitivity due to an impaired DSB repair capacity.

No effect of the transforming growth factor β1 promoter polymorphism C-509T on TGFB1 gene expression, protein secretion, or cellular radiosensitivity.

p53 modulates homologous recombination at I-SceI-induced double-strand breaks through cell-cycle regulation.

The absence of Ku but not defects in classical non-homologous end-joining is required to trigger PARP1-dependent end-joining

Sorafenib sensitizes head and neck squamous cell carcinoma cells to ionizing radiation

DNA damage by X-rays and their impact on replication processes.

Association of single nucleotide polymorphisms in the genes ATM, GSTP1, SOD2, TGFB1, XPD and XRCC1 with risk of severe erythema after breast conserving radiotherapy.

In tumor cells regulation of DNA double strand break repair through EGF receptor involves both NHEJ and HR and is independent of p53 and K-Ras status.