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Therapeutic shutdown of HBV transcripts promotes reappearance of the SMC5/6 complex and silencing of the viral genome in vivo
2022 - Forschungsinformationssystem des UKE - frei zugänglich
Efficacy of NVR 3-778, Alone and in Combination With Pegylated Interferon, vs Entecavir in uPA/SCID Mice With Humanized Livers and HBV Infection
2018 - Forschungsinformationssystem des UKE
Heme oxygenase-1 polymorphisms can affect HCV replication and treatment responses with different efficacy in humanized mice
2017 - Forschungsinformationssystem des UKE
Serum HBV pgRNA as a clinical marker for cccDNA activity
2017 - Forschungsinformationssystem des UKE
A Slow Maturation Process Renders Hepatitis B Virus Infectious
2016 - Forschungsinformationssystem des UKE
Primary Human Hepatocytes Repopulate Livers of Mice After In Vitro Culturing and Lentiviral-Mediated Gene Transfer
2016 - Forschungsinformationssystem des UKE
Hepatitis Delta co-infection in humanized mice leads to pronounced induction of innate immune responses in comparison to HBV mono-infection
2015 - Forschungsinformationssystem des UKE
Experimental Models: Cell Culture and Animal Models
2015 - Forschungsinformationssystem des UKE
Selective induction of apoptosis by HMG-CoA reductase inhibitors in hepatoma cells and dependence on p53 expression.
2012 - Forschungsinformationssystem des UKE
Strong antiviral activity of the new l-hydroxycytidine derivative, l-Hyd4FC, in HBV-infected human chimeric uPA/SCID mice.
2012 - Forschungsinformationssystem des UKE
IFN-α inhibits HBV transcription and replication in cell culture and in humanized mice by targeting the epigenetic regulation of the nuclear cccDNA minichromosome.
2012 - Forschungsinformationssystem des UKE
Humanized chimeric uPA mouse model for the study of hepatitis B and D virus interactions and preclinical drug evaluation.
2012 - Forschungsinformationssystem des UKE
Primary human hepatocytes from metabolic-disordered children recreate highly differentiated liver-tissue-like spheroids on alginate scaffolds.
2012 - Forschungsinformationssystem des UKE
RGB marking facilitates multicolor clonal cell tracking.
2011 - Forschungsinformationssystem des UKE
Hepatitis B virus limits response of human hepatocytes to interferon-α in chimeric mice.
2011 - Forschungsinformationssystem des UKE
In vivo proliferation of hepadnavirus-infected hepatocytes induces loss of covalently closed circular DNA in mice.
2010 - Forschungsinformationssystem des UKE
[Knowledge about HBV, prevention behaviour and treatment adherence of patients with chronic hepatitis B in a large referral centre in Germany].
2010 - Forschungsinformationssystem des UKE
Prevention of hepatitis B virus infection in vivo by entry inhibitors derived from the large envelope protein.
2008 - Forschungsinformationssystem des UKE
Sequential combination therapy leads to biochemical and histological improvement despite low ongoing intrahepatic hepatitis B virus replication.
2008 - Forschungsinformationssystem des UKE
Virion half-life in chronic hepatitis B infection is strongly correlated with levels of viremia.
2008 - Forschungsinformationssystem des UKE

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Therapeutic shutdown of HBV transcripts promotes reappearance of the SMC5/6 complex and silencing of the viral genome in vivo

Efficacy of NVR 3-778, Alone and in Combination With Pegylated Interferon, vs Entecavir in uPA/SCID Mice With Humanized Livers and HBV Infection

Heme oxygenase-1 polymorphisms can affect HCV replication and treatment responses with different efficacy in humanized mice

Serum HBV pgRNA as a clinical marker for cccDNA activity

A Slow Maturation Process Renders Hepatitis B Virus Infectious

Primary Human Hepatocytes Repopulate Livers of Mice After In Vitro Culturing and Lentiviral-Mediated Gene Transfer

Hepatitis Delta co-infection in humanized mice leads to pronounced induction of innate immune responses in comparison to HBV mono-infection

Experimental Models: Cell Culture and Animal Models

Selective induction of apoptosis by HMG-CoA reductase inhibitors in hepatoma cells and dependence on p53 expression.

Strong antiviral activity of the new l-hydroxycytidine derivative, l-Hyd4FC, in HBV-infected human chimeric uPA/SCID mice.

IFN-α inhibits HBV transcription and replication in cell culture and in humanized mice by targeting the epigenetic regulation of the nuclear cccDNA minichromosome.

Humanized chimeric uPA mouse model for the study of hepatitis B and D virus interactions and preclinical drug evaluation.

Primary human hepatocytes from metabolic-disordered children recreate highly differentiated liver-tissue-like spheroids on alginate scaffolds.

RGB marking facilitates multicolor clonal cell tracking.

Hepatitis B virus limits response of human hepatocytes to interferon-α in chimeric mice.

In vivo proliferation of hepadnavirus-infected hepatocytes induces loss of covalently closed circular DNA in mice.

[Knowledge about HBV, prevention behaviour and treatment adherence of patients with chronic hepatitis B in a large referral centre in Germany].

Prevention of hepatitis B virus infection in vivo by entry inhibitors derived from the large envelope protein.

Sequential combination therapy leads to biochemical and histological improvement despite low ongoing intrahepatic hepatitis B virus replication.

Virion half-life in chronic hepatitis B infection is strongly correlated with levels of viremia.