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Medientyp
- Text 2
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- Balabanov, Stefan 2
- Bokemeyer, Carsten 2
- Brümmendorf, Tim
- Fiedler, Walter
- Gontarewicz, Artur 2
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Simultaneous targeting of Aurora kinases and Bcr-Abl kinase by the small molecule inhibitor PHA-739358 is effective against imatinib-resistant BCR-ABL mutations including T315I.
- Gontarewicz, Artur
- Balabanov, Stefan
- von Amsberg, Gunhild
- Colombo, Riccardo
- Graziano, Alessio
- Pesenti, Enrico
- Benten, Daniel
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PHA-680626 exhibits anti-proliferative and pro-apoptotic activity on Imatinib-resistant chronic myeloid leukemia cell lines and primary CD34+ cells by inhibition of both Bcr-Abl tyrosine kinase and Aurora kinases.
- Gontarewicz, Artur
- Balabanov, Stefan
- von Amsberg, Gunhild
- Panse, Jens
- Schafhausen, Philippe
- Bokemeyer, Carsten
- Fiedler, Walter